Non-HIV AIDS presenting with adrenal histoplasmosis and pulmonary tuberculosis: a mesmerising case report and discussion

Arnab Banerjee; Mithun Biswas; Niladri Sarkar

doi:10.18203/2320-6012.ijrms20150652

Authors

Arnab Banerjee Department of Internal Medicine, IPGMER, Kolkata
Mithun Biswas Department of Anaesthesiology, NRSMCH, Kolkata
Niladri Sarkar Department of Internal Medicine, IPGMER, Kolkata

DOI:

https://doi.org/10.18203/2320-6012.ijrms20150652

Keywords:

Non-HIV AIDS, Idiopathic CD4 lymphocytopenia, Adrenal histoplasmosis, Tuberculosis, Immunosuppression, Adrenal failure

Abstract

Non-HIV AIDS or idiopathic CD4 lymphocytopenia (ICL) is an acquired immunodeficiency syndrome resulting in CD4 lymphopenia without any evidence of HIV infection or any other apparent cause of immunosuppression. A non-diabetic patient presented with adrenal histoplasmosis and UTI leading to adrenal failure. No immediate cause of immunosuppression was found, HIV, HTLV screening were negative. A CD4 count was done and the patient was found to be having non-HIV AIDS (idiopathic CD4 lymphocytopenia). He was treated and discharged. Few months later the patient presented again with adrenal failure & pulmonary tuberculosis. Adrenal FNAC showed persisting adrenal histoplasmosis. CD4 count found to be low again, but this time it was worse than the previous scenario.

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