Published: 2017-01-12

Giant fibrosarcoma of anterior abdominal wall: a rare case report and review literature

Jeewan Ram Vishnoi, Channabasappa Kori, Saumya Shukla, Sameer Gupta, Vijay Kumar, Shiv Rajan


Adult type fibrosarcoma is very rare malignant soft tissue tumor. It usually arises in soft tissues of extremities, trunk, head and neck. Fibrosarcoma is essentially a diagnosis of exclusion from other spindle cell mesenchymal malignant neoplasm; by definition negative for epithelial, myogenous and neural markers on immunohistochemistry. To the best of our knowledge, very few cases have been reported in the literature. We here report a case of giant fibrosarcoma arising from anterior abdominal wall in a recurrent dermatofibrosarcoma proturbens and managed with surgical excision and reconstruction with meshplasty.  


Giant fibrosarcoma, Adult fibrosarcoma, Abdominal wall

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Singer S, Maki RG, O’Sullivan B. Soft tissue sarcoma. In: DeVita, Hellman, Rosenberg, eds. Cancer: Principles and Practice of Oncology. 9th ed. Philadelphia PA, USA: Lippincott Williams & Wilkins; 2011: 1522-1609.

Fisher C, van den Berg E, Molenaar WM. Adult fibrosarcoma. In: Fletcher CDM, Unni KK, Mertens F, eds. World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon, France: IARC Press; 2002: 100–101.

Cozzolino I, Caleo A, Di Crescenzo V, Cinelli M, Carlomagno C, Garzi A, et al. Cytological diagnosis of adult-type fibrosarcoma of the neck in an elderly patient. Report of one case and review of the literature. BMC Surg. 2013;13(Suppl 2):S42.

Bahrami A, Folpe AL. Adult-type fibrosarcoma: a reevaluation of 163 putative cases diagnosed at a single institution over a 48-year period. Am J Surg Pathol. 2010;34(10):1504-13.

Man H. Shiu, Laurence Weinstein, Steven I. Hajdu, Murray F. Brennan. Malignant soft tissue tumours of the anterior abdominal wall. AMJ Surg. 1989;152:416-51.

Fletcher CDM, Krishnan Unni K, Mertens F. Pathology and genetics of tumours of soft tissue and bone (IARC WHO Classification of Tumours). Adult fibrosarcoma. Geneva: WHO; 2006: 4.

Folpe AL. Fibrosarcoma: a review and update. Histopathology. 2014;64:12-25.

Coindre JM. Immunohistochemistry in the diagnosis of soft tissue tumours. Histopathology. 2003;43(1):1-16.

Heim-Hall J, Yohe SL. Application of immunohistochemistry to soft tissue neoplasms. Arch Pathol Lab Med. 2008;132:476-89.