A study of clinical profile of frailty in elderly patients attending KIMS teaching hospital, Koppal

Srinivasa J.; Tamberi Tejaswini; Gavishiddesh V. Ronad; Shivaprasada T.

doi:10.18203/2320-6012.ijrms20264191

Authors

Srinivasa J. Department of General Medicine, KIMS, Koppal, Karnataka, India
Tamberi Tejaswini Department of General Medicine, Sri Venkateshwara, Institute of Medical Science, Andhra Pradesh, India
Gavishiddesh V. Ronad Department of General Medicine, KIMS, Koppal, Karnataka, India
Shivaprasada T. Department of General Medicine, KIMS, Koppal, Karnataka, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20264191

Keywords:

Frailty, Elderly, Geriatric assessment, Fried frailty phenotype, Tertiary care hospital

Abstract

Background: Frailty is a common geriatric syndrome associated with increased vulnerability to adverse health outcomes. Early identification is important for improving care among elderly populations. Objectives were to assess the clinical profile of frailty and identify factors associated with frailty among elderly patients attending a tertiary care teaching hospital in Koppal, Karnataka.

Methods: This prospective observational study was conducted over 18 months at KIMS Teaching Hospital, Koppal, among 100 patients aged ≥65 years. Frailty was assessed using the Fried frailty phenotype criteria. Demographic, socioeconomic, comorbidity, and functional data were collected and analyzed using descriptive statistics, bivariate analysis, and multinomial logistic regression.

Results: Among participants, 11% were robust, 52% pre-frail, and 37% frail. Frail participants were significantly older (p=0.013), with a higher proportion aged ≥70 years (p=0.008). Weak grip strength (73%) and reduced physical activity (48%) were the most common frailty components. Educational status (p=0.002), living arrangement (p=0.038), and income level (p<0.001) were significantly associated with frailty. Increasing age independently predicted frailty (OR=1.32, p=0.038), while hypertension showed a protective association (OR=0.07, p=0.039).

Conclusions: Frailty and pre-frailty were highly prevalent. Routine frailty screening may support early identification and targeted interventions.

References

Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56(3):M146-56.

World Health Organization. World report on ageing and health. Geneva: World Health Organization. 2015.

Biritwum RB, Minicuci N, Yawson AE, Theou O, Mensah G, Naidoo N, et al. Prevalence of frailty and associated factors among older adults in low- and middle-income countries: a systematic review and meta-analysis. Age Ageing. 2016;45(6):746-54.

Bandeen-Roche K, Seplaki CL, Huang J, Buta B, Kalyani RR, Varadhan R, et al. Frailty in older adults: a nationally representative profile in the United States. J Gerontol A Biol Sci Med Sci. 2015;70(11):1427-34.

Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K. Frailty in elderly people. Lancet. 2013;381(9868):752-62.

Shilpa M, Kumar SG, Naik PR, Ashok NC. Prevalence of frailty and its association with socio-demographic factors among elderly in a rural area of Karnataka. J Family Med Prim Care. 2020;9(9):4766-71.

Hoogendijk EO, Afilalo J, Ensrud KE, Kowal P, Onder G, Fried LP. Frailty: implications for clinical practice and public health. Lancet. 2019;394(10206):1365-75.

Apóstolo J, Cooke R, Bobrowicz-Campos E, Santana S, Marcucci M, Cano A, et al. Effectiveness of interventions to prevent pre-frailty and frailty progression in older adults: a systematic review. JBI Database System Rev Implement Rep. 2018;16(1):140-232.

Collard RM, Boter H, Schoevers RA, Oude Voshaar RC. Prevalence of frailty in community-dwelling older persons: a systematic review. J Am Geriatr Soc. 2012;60(8):1487-92.

Siriwardhana DD, Hardoon S, Rait G, Weerasinghe MC, Walters KR. Prevalence of frailty and prefrailty among community-dwelling older adults in low-income and middle-income countries: a systematic review and meta-analysis. BMJ Open. 2018;8(3):e018195.

Mitnitski A, Song X, Rockwood K. The estimation of relative fitness and frailty in community-dwelling older adults using self-report data. J Gerontol A Biol Sci Med Sci. 2004;59(6):M627-32.

Gordon EH, Peel NM, Samanta M, Theou O, Howlett SE, Hubbard RE. Sex differences in frailty: a systematic review and meta-analysis. Exp Gerontol. 2017;89:30-40.

Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16-31.

Odden MC, Peralta CA, Haan MN, Covinsky KE. Rethinking the association of high blood pressure with mortality in elderly adults: the impact of frailty. Arch Intern Med. 2012;172(15):1162-8.

Stringhini S, Sabia S, Shipley M, Brunner E, Nabi H, Kivimaki M, et al. Association of socioeconomic position with health behaviors and mortality. JAMA. 2010;303(12):1159-66.

Kim S, Brooks AK, Groban L. Prevalence of frailty in older adults and its association with socioeconomic status: a systematic review. BMC Geriatr. 2018;18(1):1-12.

Gale CR, Westbury L, Cooper C. Social isolation and loneliness as risk factors for the progression of frailty: the English Longitudinal Study of Ageing. Age Ageing. 2018;47(3):392-7.