Published: 2017-01-14

A study of risk factors in young patients of myocardial infarction

Mohd Vaseem Akram, Farina Zaidi, Shivani Bansal, Kaushal Kishore


Background: Coronary Artery Disease (CAD) is the major cause of morbidity and mortality burden in the world. Young patients with CAD are specific subset of population requiring attention. A variety of possible contributing factors  that include substance abuse, coronary artery anomalies, hypercoagulablestate, oral contraceptive use in young women have been implicated for the pathogenesis of myocardial infarction. The purpose of this study is to collect data of young patients presenting with AMI so that it would be helpful in future for better management in this particular group of patients. Aim of the present investigation was to study clinical profile of acute myocardial infarction in young patients 18-45 years of age and to study the incidence of various risk factors in young patients with myocardial infarction.

Methods: The study was conducted in Department of medicine of Santosh medical college & hospital. Study was conducted on 50 cases of acute myocardial infarction if they satisfied the following selection criteria after getting formal consent and ethical clearance.

Results: In our study, we have examined patients of myocardial infarction who are aged between 18-45 yrs. and other eligibility criteria for the assessment of modifiable and non-modifiable risk factors in Ghaziabad area. The ratio of male to female sex ratio in our study is 5.25:1 and 64% of the patients in present study had anterior wall MI while 24% had inferior wall MI and 12% had antero-septal wall MI.

Conclusions: Mean age of study group is 36.24 ±4.32 years. The maximum number of patients was in 35-40 years of age. Youngest patient was 25 years old male. The incidence of acute myocardial infarction is increasing in younger age group.



Myocardial infarction in young patients

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Bahl VK, Prabhakaran D, Karthikeyan G; Coronary Artery disease in Indians. IHJ Nov-Dec 2001.

Rissan HS, Kishore S, Trehan N; Coronary Artery disease in young Indians: The Missing Link. JIACM, Volume 2 (3), 2001.

Eugene Braun Wald, Joseph Loscalzo; Ischaemic Heart Diseases; Harrison’s Principle of Internal Medicine 18th Edition, Mc Graw Hill, 2008. 12. Henry N. Ginsberg, Ira J. Goldberg: Disorder of Lipoprotein metabolism in Harrison’s Principles of Internal Medicine, 18th Ed, E. Braun Wald et al, Mc Graw Hill, 2008.

Leo Schamroth; Myocardial Infarction; An Introduction to Electrocardiography 7th Edition, Blackwell.

Jo Anne Micaly Foody: Cardiovascular risk factors: Manual of Cardiovascular Medicine, 2nd Ed. Brian. P. Griffin, Eric J. Topol. (Eds.), Lippincott Williams and Wilkins, Philadelphia, 2004.

Joshi SR, Joshi SS. Obesity therapeutics- the Indian consensus in medicine updates 2002, vol 12.

Osula S, Bell GM, Hornung RS. Acute Myocardial infarction in young adults: causes and management; Post grad Med J. 2002;78;27-30.

Dwiwedi S, Dwiwedi G, Sharma S: Coronary artery disease in young: Heredofemilial or Faculty Life Style or both. JIACM. 2000, 1(3),245-51.

Dani SI, Ghosh SB, Prajapati JS, Jain S; Clinical and coronary Angiographic profile of Coronary Artery Disease in a young Gujarati population. IHJ Sept-Oct 2003.

Wasir HS, Bharani AK, et al. Correlation of risk factor with coronary angiographic finding in patients of ischemic heart disease. JAPI 1987;36(7):483-7.

Poberto Malacrida et al: Epidemiology variables and outcome of 1972 young patients with Acute Myocardial infarction, Arch Intern Med; 1997,157, Page 865-869.

Garg KC, Negi NS, et al. Acute myocardial infarction in young adults. JAPI 1987, Vol 35, No. 4, P 281-284.

Donald A. Underwood et al: Symptomatic coronary artery disease in patients aged 21-30 years. Am J Cardiology. 1985;55:631-4.

S.B. Siwach et al; Profile of young Acute Myocardial Infarction in Haryana JAPI. 1998;46(5):424-26.

P. Jit Singh et al: Myocardial infarction in young- A Study of 42 cases. JAPI. 2001;49:32.