Prevalence of diabetes mellitus in tuberculosis patients: a hospital based study


  • Manoj D. Kottarath Department of Pulmonary Medicine, Academy Of Medical Sciences, Pariyaram, Kerala
  • Rajani Mavila Department of Pulmonary Medicine, Academy Of Medical Sciences, Pariyaram, Kerala
  • Achuthan V. Department of Pulmonary Medicine, Academy Of Medical Sciences, Pariyaram, Kerala
  • Smitha Nair Department of Pulmonary Medicine, Academy Of Medical Sciences, Pariyaram, Kerala



Tuberculosis, Diabetes mellitus, Fasting plasma glucose, Sputum positive pulmonary tuberculosis


Background: Screening of high risk individuals with weak immunity as in diabetics for active tuberculosis is of great public health importance. The prevalence of diabetes in tuberculosis is high and the data regarding the same is necessary for strengthening TB control activities.

Methods: This study was conducted to know the prevalence of diabetes mellitus in tuberculosis patients diagnosed from the hospital. This was a hospital based descriptive study conducted in Department of Respiratory medicine, Academy of Medical Sciences, Northern Kerala in association with DOTS center during a one year period from August 2014 to July 2015. All patients diagnosed as a case of tuberculosis from our institution were included for the study. All patients were screened for diabetes mellitus using Fasting Plasma Glucose value. Additional information regarding age, body mass index (BMI), sputum smear positivity and treatment category of tuberculosis were collected.

Results: There was a higher prevalence of diabetes in tuberculosis patients than in general population and the rate was found to be 19.6%. There was a statistically significant association of diabetes with older age, higher BMI and sputum positivity.

Conclusions: Routine screening for diabetes needs to be intensified in the community and more importantly in Tuberculosis patients.



WHO: Global Tuberculosis Report-2014. Accessed on 10, September 2015.

Joshi SR, Parikh RM. India - diabetes capital of the world: now heading towards hypertension. J Assoc Physicians India. 2007;55:323-4.

Kumar A, Goel MK, Jain RB, Khanna P, Chaudhary V. India towards diabetes control: Key issues. Australas Med J. 2013;6(10):524-31.

Ramachandran A. Epidemiology of diabetes in India: three decades of research. J Assoc Physicians India. 2005;53:34-8.

Baker MA, Harries AD, Jeon CY, Hart JE, Kapur A, et al. The impact of diabetes on tuberculosis treatment outcomes: A systematic review. BMC Med. 2011;9:81.

IUATLD & WHO: Collaborative Framework for Care& Control of Tuberculosis and Diabetes. Accessed on September 10, 2015.

Balakrishnan S, Vijayan S, Nair S, Subramoniapillai J, Mrithyunjayan S, Wilson N, et al. High diabetes prevalence among tuberculosis cases in Kerala, India. PLoS One. 2012;7:e46502.

Global Database on Body Mass Index. World Health Organization, 2006. Accessed on September 10, 2015.

Definition and diagnosis of diabetes mellitus and intermediate hyperglycaemia: Report of a WHO/IDF consultation. Geneva: WHO. September 10, 2015.

Central TB Division, GOI-WHO Collaboration Programme (2008-09), Revised National Tuberculosis Control Programme-Training Course for Program Manager (Modules 1-4). 2011:22-29.

Kutty VR, Soman CR, Joseph A, Pisharody R, Vijayakumar K. Type 2 diabetes in southern Kerala: variation in prevalence among geographic divisions within a region. Natl med J Ind. 2000;13:287-92.

Screening of Tuberculosis Patients for Diabetes Mellitus: Pilot Project-Module for RNTCP staff 2009.Central TB Division, MOH & FW, New Delhi

Raghuraman S, Vasudevan KP, Govindarajan S, Chinnakali P, Krishna Chandra Panigrahi. Prevalence of Diabetes Mellitus among Tuberculosis Patients in Urban Puducherry N Am J Med Sci. 2014;6(1):30-4.

Singla R, Khan N, Al-Sharif N, Al-Sayegh MO, Shaikh MA, Osman MM. Influence of diabetes on manifestations and treatment outcome of pulmonary TB patients. Int J Tuberc Lung Dis. 2006;10:74-9.

Jain MK, Baghel PK, Agrawal R. Study of impaired glucose tolerance in pulmonary tuberculosis. Indian J Community Med. 2006;31(3):137-9

Alisjahbana B, Sahiratmadja E, Nelwan EJ, Purwa AM, Ahmad Y, Ottenhoff TH, et al. The effect of type 2 diabetes mellitus on the presentation and treatment response of pulmonary tuberculosis. Clin Infect Dis. 2007;45:428-35.

Chang JT, Dou HY, Yen CL, Wu YH, Huang RM, Lin HJ, et al. Effect of type 2 diabetes mellitus on clinical severity and treatment outcome in patients with pulmonary tuberculosis: A potential role in the emergence of multi-drug resistance. J Formos Med Assoc. 2011;110:372-81.

Guptan A, Shah A. Tuberculosis and Diabetes: An Appraisal. Ind J Tub. 2000;47(3):2-8.

World Health Organization. Obesity and Overweight Facts. Available at Accessed on 10 September 2015.

Mi F, Tan S, Liang L, Harries AD, Hinderaker SG, Lin Y, et al. Diabetes mellitus and tuberculosis: pattern of tuberculosis, two-month smear conversion and treatment outcomes in Guangzhou, China. Tropical Medicine & International Health. 2013;18:1379-85.




How to Cite

Kottarath, M. D., Mavila, R., V., A., & Nair, S. (2017). Prevalence of diabetes mellitus in tuberculosis patients: a hospital based study. International Journal of Research in Medical Sciences, 3(10), 2810–2814.



Original Research Articles