Organophosphorous intoxication and hyperthyroidism

Authors

  • Bhavana Nagabhushana Rao Department of General Medicine, NRI Hospital, Seethammadhara, Visakhapatnam, Andhra Pradesh
  • Raman Bhavana Department of General Surgery, NRI Hospital, Seethammadhara, Visakhapatnam, Andhra Pradesh

DOI:

https://doi.org/10.18203/2320-6012.ijrms20150841

Keywords:

Organophosphorus intoxication, Hyperthyroidism, Atropinisation, Tachyarrhythmia

Abstract

It is well established that transient thyroid dysfunction can occur in many non-thyroid illness. But abnormal thyroid function test in the range of hyperthyroidism is not reported many a times. Here we present two cases of chlorpyrifos intoxication presenting with hyperthyroidism and its implications in the management of the patient in acute illness.

Role of atropine in antagonizing muscarinic effects of organophosphorus intoxication is well documented. Interplay between atropine, hyperthyroid state and tachycardia discussed.

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References

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Eddleston M, Dawson A, Karalliedde L, et al. Early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors. Critical Care. 2004;8(6):R391-R397.

Lacasaña M, López-Flores I, Rodríguez-Barranco M, Aguilar-Garduño C, Blanco-Muñoz J, Pérez-Méndez O, et al. Interaction between organophosphate pesticide exposure and PON1 activity on thyroid function. Toxicol Appl Pharmacol. 2010;249(1):16-24.

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Published

2017-01-14

How to Cite

Rao, B. N., & Bhavana, R. (2017). Organophosphorous intoxication and hyperthyroidism. International Journal of Research in Medical Sciences, 3(10), 2857–2859. https://doi.org/10.18203/2320-6012.ijrms20150841

Issue

Section

Case Reports