Effects of laser therapy on chronic skin ulcers healing interventions for Sudanese patients

Abdelrazig M. Abdelbagi, Masher M. Yousif, Shaza M. Yousif, Mahaseen M. Baloo


Background: The purpose of this study is attempting to the assessment of the effectiveness of low level laser therapy (LLLT) with specific parameters in the treatment of selected Sudanese patients based on clinical records of different skin ulcers and diabetic's wounds in Khartoum state hospitals. Thus, the effect of the laser treatment using bio - stimulation effects on tissues in infrared laser and in the visible region depends on frequencies, power density and time of exposure rate on skin diseases.

Methods: It is prospective clinical descriptive, interventional study on seven selected males and females of different ages depend on clinical and positive smear LD bodied, which was confirmed at Omdurman tropical disease hospital. Low power laser Omega-XP with tunable wavelengths 820 nm, 780 nm, 675 nm and constant parameters were applied for medical treatment.

Results: Utilization of laser dosage (energy density) of 40 J/cm2 and 1.6 w/cm2 power density of the wavelength 820 nm and 30 J/cm2 energy density and power density of 0.24 w/cm2 of 780 nm wavelength, in addition to energy density of 8 J/cm2 and power density of 0.24 w/cm2 and 0.40 w/cm2 and energy density of 1.6 J/cm2 for the 675 wavelength was applied. In this study, we used the bio-stimulation effect of LLLT to enhance healing through immune modulation. However, the application of low level diode laser in the treatment of diabetic wounds can be accompanied by low energy density and short wavelength to give better results in a short time and a good diagnostic accuracy for its potentiality in the field.

Conclusions: Consequently, the brown skins in Sub-Saharan region for different tissues of Sudanese diabetic patients of chronic skin ulcer can be treated with different wavelengths and energy relative to tissues softening  and laser parameters of that optimum values were obtained. The assessment of skin regeneration using laser therapy expose that the quality of growth, the reasonable period of healing and decreases the risk skin infection were achieved. The process of diabetic wounds curing and de-pigmentation, potential resident of decreasing pain and an efficient adjunct to a standard wound management was obtained.



Low level laser therapy, Skin ulcer, Pigmentation, Laser power, Fluence

Full Text:



Tanaka Y, Matsuo K, Yuzuriha S. Objective assessment of skin rejuvenation using near-infrared 1064-nm neodymium, scientific and medical research. Clinical, Cosmetic and Investigational Dermatology ( YAG laser in Asians. 2011;123-130.

Karsten AE. Effect of Wavelength, Epidermal Thickness and Skin Type on the Required Dose for Photodynamic Therapy. International Conference of the World Association of Laser Therapy; WALT. 2008;137-43.

Saeedur Rahman, Fatima Humera Abdullah, Jamshaid Ali Khan, the frequency of old world Cutaneous Leishmaniasis in skin Ulcers in Peshawar. Journal of Ayub Medical College Abbottabad. 2009;21(3):72-5.

Bresler A, Hawkins D, Razlog R, Abrahamse H. Effect of Low Level Laser Therapy and Calendula officinalis 3 CH on Wound Healing in Human Skin Fibroblasts, Home Opathic research. AJHM Summer. 2007;100:110-8.

Lam LK, Cheing GL. Effects of 904 nm Low Level laser therapy in the management of Lateral epicondylitis: a randomized controlled trial, Photomed laser Surg. Laser therapy literature, Swedish Laser Medical Society. 2007;25(2):65-7.

Geiges ML, Bogdan AI, Goldberg DJ, eds. History of Lasers in Dermatology, In: Basics in Dermatological Laser Applications. Curr Probl Dermatol. Basel, Karger. 2011;42:1–6.

Elizabeth. Laser in dermatology four decade of progress. J Am Acad Dermatology. 2003:1-31.

Guillermo Arguilar Lars O. Svaasand and J. Stuart Nelson. Effects of Hypobaric pressure on human skin, Feasibility study for port wine strain laser therapy (Part 1). Laser in Surgery Medicince. 2005;36:124-9.

Harding. Evidence for Variable Selective Pressures at MC1R. The American Journal of Human Genetics. 2000;66(4)51–61.

Jablonski, N; Chaplin, G (2000). "The evolution of human skin coloration". Journal of Human Evolution 2000; 39(1) 57–106.

Houreld N, Ablahamse. Photomed In Vitro Exposure of wounded diabetic fibroblast cells to a helium-neon Laser at 5 to 16 J/cm2.Laser world, Swedish laser medical society Photomed Laser. 2007;25(2):78-84.

Grace Wang. Low level laser therapy (LLLT) Technology Assessment. Laser world, Swedish Laser Medical Society; 2004.

Epitomes important advance in clinical medicine, Dermatology Reprint requests to Division of Scientific and Educational Activities, California Medical Association. The western journal of medicine. 1987;147(4) 456-7.

Daniel Barolet, MD. Light-Emitting Diodes (LEDs) in Dermatology. Semin Cutan Med Surg, Elsevier Inc. 2008;227-38.

Relethford, JH. Human skin color diversity is highest in sub-Saharan African populations. Human biology; an international record of research. 2000;72(5)773–80.

Holick, Michael F. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. The American journal of clinical nutrition. 2004;80 (6) 1678S–88S.

Millington, G W M Proopiomelanocortin (POMC): the cutaneous roles of its melanocortin products and receptors. Clinical and Experimental Dermatology. 2006;31(3)407–12.

Istvan Stadler, Ramond J. Lanzafame, Melanin density affect photobiomodulation outcomes in cell culture. photomed laser surg. 2007;25(3)144-9.

Jablonski NG, Chaplin G. "Skin Deep". Scientific American. 2002;287(4):74–82.

Devin Houston. The Basics of Digestive Enzymes as Dietary Supplements Houston Nutraceuticals, Inc. 2007;1-5.