Comparative study of dry eye after Phacoemulsification in senile cataract


  • Manisha Gupta Department of Ophthalmology, Sri Guru Ram Rai Institute of Medical and Health Sciences Patel Nagar, Dehradun
  • Sanjeev Mittal Department of Ophthalmology, Sri Guru Ram Rai Institute of Medical and Health Sciences Patel Nagar, Dehradun
  • Tarannum Shakeel Department of Ophthalmology, Sri Guru Ram Rai Institute of Medical and Health Sciences Patel Nagar, Dehradun
  • Renu Gupta Department of Ophthalmology, Sri Guru Ram Rai Institute of Medical and Health Sciences Patel Nagar, Dehradun



Schirmer1 test, Fluorescein tear break-up time, Lissamine staining


Background:Corneal surgery has been identified as one of the risk factors for the development of dry eye disease by decreasing corneal sensation and changing the contour of the ocular surface as a result of the inflammation caused by surgical trauma. Clear cornea phacoemulsification may also alter the ocular surface and disrupts normal tear function in eyes.  The  purpose  of  study  to  compare  dry eye  caused  by phacoemulsification   in  different  age  groups  in senile cataract  patient with no pre-existing  dry eye.

Methods: After  taking  informed  consent  50  eyes  of  50 patient  of  senile  cataract  with  no preoperative  dry eye  had  under gone   2.75 mm  superior clear corneal phacoemulsification  with  IOL implantation.  After ruling out  pre-existing  ocular disease, surgery ,trauma and systemic diseases, Dry  Eye  evaluation by  schirmer1test , FTBUT and  lissamine  conjunctival  staining was done pre and  postoperatively at 1st ,4th and  12th week .

Data was collected and analysed on IBM SPSS version 23 by paired T test.

Results: In all age group, S1T and FTBUT, conjunctival staining showed   lowest   values at 1stweek (p <0.05) and by 12th week values has come near to base line value (p <0.05). Results showed only 38% of cases in 45-55 age group, 50% in 56-65 age group and all the cases showed dry eye in 66-75 age group at 12th week.

Conclusions: We  have concluded that  phacoemulsification  surgery  affects  the  tear  film  stability and the  production of tears postoperatively and causes  dry  eye  more  in  the  older  age  group.



Lemp MA, Baudouin C, Baum J, et al. The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye Workshop. Ocular Surf. 2007;5:75-92.

Apostol S, Filip M, Dragne C, Filip A. Dry eye syndrome; etiological and therapeutic aspects. Oftalmologia. 2003;59:28-31.

Shoja MR, Besharati MR. Dry eye after LASIK for myopia: incidence and risk factors. Eur J Ophthalmol. 2007;17:1-6.

Moss SE, Klein R, Klein BE. Long-term incidence of dry eye in an older population. Optom Vis Sci. 2008;85:668-74.

De Paiva CS, Chen Z, Koch DD, Hamill MB, Manuel FK, Hassan SS et al. The incidence and risk factors for developing dry eye after myopic LASIK. Am J Ophthalmol. 2006;141:438-45.

Murube J, Wilson S, Ramos-Esteban J. New horizons in the relief and control of dry eye. Highlights Opthalmol. 2001;26:55-64.

Schaumberg DA, Sullivan DA, Buring JE, Dana MR. Prevalence of dry eye syndrome among US women. Am J Ophthalmol. 2003;136:318-26.

Moss SE, Klein R, Klein BE. Prevalence of and risk factors for dry eye syndrome. Arch Ophthalmol. 2000;118:1264-8.

Schaumberg DA, Dana R, Buring JE, Sullivan DA. Prevalence of dry eye disease among US men: Estimates from the Physicians′ Health Studies. Arch Ophthalmol. 2009;127:763-8.

Benitez-del-Castillo JM, Rio DT, Iradier T et al. Decrease in tear secretion and corneal sensitivity after laser-in-situ keratomileusis. Cornea .2001;20: 30-2.

Nassaralla BA, McLeod SD, Nassaralla JJ Jr. Effect of myopic LASIK on human corneal sensitivity. Ophthalmology. 2003;110:497-502.

Albietz JM, Lenton LM. Management of the ocular surface and tear film before, during, and after laser-in-situ keratomileusis. J Refract Surg. 2004;20:62-4.

Liu Z, Luo L, Zhang Z et al. Tear film changes after phacoemulsification. Zhonghua Yan Ke Za Zhi. 2002;38:274- 6.

Pisella PJ, Pouliquen P, and Baudouin C. Prevalence of ocular symptoms and signs with preserved and preservative-free glaucoma medication. Br J Ophthalmol. 2002;86:418-23.

Garcia-Catalan MR, Jerez-Olivera E, Benitez-Del-Castillo-Sanchez JM. Dry eye and quality of life. Arch Soc Esp Oftalmol. 2009;84:451-8.

Nistor MC, Nistor C. Clinical correlations between dry eye and cataract surgery. Oftalmologia .2007; 51:79-82.

Ishibashi T, Yokoi N, Kinoshita S. Comparison of short-term effects on the human corneal surface of topical timolol maleate with and without benzalkonium chloride. J Glaucoma. 2003;12:486-90.

Calvillo MP, McLaren JW, Hodge DO, et al. Corneal reinnervation after LASIK: prospective 3-year longitudinal study. Invest Ophthalmol. Vis Sci 2004;4:3991-6.

Donnenfeld ED, Solomon K, Perry HD. The effect of hinge position on corneal sensation and dry eye after LASIK. Ophthalmology.2003;110:1025-7.

Belmonte C, Acosta MC, Gallar J. Neural basis of sensation in intact and injured corneas. Exp Eye Res. 2004;78:513-25.

Sitompul R, Sancoyo GS, Hutauruk JA et al. Sensitivity change in cornea and tear layer due to incision difference on cataract surgery with either manual small incision cataract surgery or phacoemulsification. Cornea .2008;27;13-8.

Mathers WD. Why the eye becomes dry: a cornea and lacrimal gland feedback model. CLAO J. 2000;26:31.

Sheppard JD. Guidelines for the treatment of chronic dry eye disease. Manad Care. 2003;12(12):20-25.

Oh T, Jung Y, ChangD, ChangD, Kim J, Kim H. Changes in tear film and ocular surface after cataract surgery. Jpn J Ophthalmol. 2012;56:113-8.

Han KE, Yoon SC, Ahn JM, Nam SM, Stulting RD, Kim EK et al. Evaluation of dry eye and meibomian gland dysfunction after cataract surgery. Am J Ophthalmol. 2014;157:1144-50.

Movahedan A, Djalilian AR. Cataract surgery in the face of ocular surface disease. Curr Opin Ophthalmol. 2012;23:68-72.

El-Hawy AA. Evaluation of Different Modaleties of Phacoemulsification in Managment of Hard Cataracts. The Medical Journal of Cairo University. 2012;80(1):339-43.




How to Cite

Gupta, M., Mittal, S., Shakeel, T., & Gupta, R. (2017). Comparative study of dry eye after Phacoemulsification in senile cataract. International Journal of Research in Medical Sciences, 3(12), 3802–3807.



Original Research Articles