DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20151451

SpO2/FiO2 ratio: a prognostic marker for influenza patients

Vrinda Sahasrabhojney, Prasad D. Game, Dipti Chand, Vinay Meshram, Mahesh Kharade, Rahul Deotale

Abstract


Background: The objective of the study was to study the utility of SpO2 /FiO2 ratio for monitoring and predicting the outcome of   H1N1 positive patients of category C.

Methods: This study is a hospital based observational study done at Government Medical College, Nagpur, Maharashtra, India from 14th January to 15th April 2015.  In this study, 156 H1N1 positive patients of category C were included.

Results: 156 Patients were included. 96 were female and 60 were male patients. SpO2/FiO2 ratio was calculated on day one and values were used to divide patients into 5 groups. Highest mortality (70%) is seen in a group with SpO2/FiO2 ratio < 150. SpO2/FiO2 ratio progressively dropped in patients who died. SpO2/FiO2 ratio gradually improved in patients who survived.

Conclusions: SpO2/FiO2 ratio on day 1 can be used as a prognostic marker in H1N1 positive patients. SpO2/FiO2 ratio was found to be a reliable marker to monitor the patients.


Keywords


SpO2/FiO2 ratio, H1N1, Influenza, Prognostic marker

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References


Pneumatikos I, Papaioannou VE. The new Berlin definition: What is, finally, the Ards? Pneumon. 2012;25(4).

Seasonal Influenza A (H1N1) Guidelines on Categorization of Seasonal Influenza A H1N1 cases during screening for home isolation, testing, treatment and hospitalization, Revised on 11.02.2015 by Ministry of Health & Family Welfare of India.

Grissom CK, Brown SM, Kuttler K, Boltax JP. A Modified Sequential Organ Failure Assessment (MSOFA):Score for Critical Care Triage; Disaster Med Public Health Prep, 2010.

Vincent JL, Mendonca Ad, Cantraine F. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: Results of a multicenter, prospective study. Crit Care Med. 1998;26:1793-800.

Mortz MS. US patent 714,803,2004 pulse oximeter probe off detection system.

Rice TW, Wheeler AP, Bernard GR, Hayden DL. Ware; Comparison of the SpO2/FIO2 Ratio and the PaO2/FIO2 Ratio in Patients with Acute Lung Injury or ARDS. Chest. 2007;132:410-7.