Nonspecific interstitial pneumonia presenting with high grade fever: a case report

Authors

  • Amarjit Singh Vij Department of Medicine, Punjab Institute of Medical Sciences, Jalandhar, Punjab
  • Mohd. Younus Shah Department of Medicine, Punjab Institute of Medical Sciences, Jalandhar, Punjab
  • Navdeep Singh Department of Medicine, Punjab Institute of Medical Sciences, Jalandhar, Punjab
  • Sunil Kumar Sharma Department of Medicine, Punjab Institute of Medical Sciences, Jalandhar, Punjab
  • Amandeep Singh Department of Medicine, Punjab Institute of Medical Sciences, Jalandhar, Punjab

DOI:

https://doi.org/10.18203/2320-6012.ijrms20151461

Keywords:

Idiopathic interstitial pneumonia, Nonspecific interstitial pneumonia, Cough, Fever

Abstract

Nonspecific interstitial pneumonia (NSIP), one subtype of idiopathic interstitial pneumonias is an autoimmune disease presenting usually at a younger age, most commonly in women. It can be distinguished clinically and pathologically from other subgroups of idiopathic interstitial pneumonias. Many cases of this entity occur in the context of an underlying disorder, such as a connective tissue disease, drug induced interstitial lung disease, or chronic hypersensitivity pneumonitis. Symptoms are non-specific and include insidious onset of dyspnoea and dry cough with restrictive pattern of decreased lung function and reduced gas exchange capacity. Fever or a flu-like syndrome can occur in up to one third of patients with NSIP. We report a case of 50 years old female who presented with breathlessness, cough and high grade fever. She did not have any features suggestive of connective tissue disease. On computed tomography of chest, diagnosis of NSIP was made and she responded to steroids.

References

Nagai S, Kitaichi M, Itoh H, Nishimura K, Izumi T, Colby TV. Idiopathic nonspecific interstitial pneumonia/fibrosis: comparison with idiopathic pulmonary fibrosis and BOOP. Eur Respir J.1998; 12:1010-9.

King TE. Interstitial Lung Disease. In Harrison’s Principles of Internal Medicine 18th Edition Mc Graw Hill. 2012;2160-6.

Katzenstein A-L, Fiorelli R. Nonspecific interstitial pneumonia/fibrosis: histologic features and clinical significance. Am J Surg Pathol. 1994;18:136-47.

Travis WD, Costabel U, Hansell DM et al.An Official American Thoracic Society/European Respiratory Society Statement: Update of the International Multidisciplinary Classification of the Idiopathic Interstitial Pneumonias. Am J Respir Crit Care Med. 2013;188(6):733-48.

Park JS, Lee KS, Kim JS, et al. Nonspecific interstitial pneumonia with fibrosis: radiographic and CT findings in seven patients. Radiology. 1995;195:645-8.

Flaherty KR, Toews GB, Travis WD, Colby TV, Kazerooni EA, Gross BH, Jain A, Strawderman RL, 3rd, Paine R, Flint A et al. Clinical significance of histological classification of idiopathic interstitial pneumonia. Eur Respir J. 2002;19:275-83.

Riha RL, Duhig EE, Clarke BE, Steele RH, Slaughter RE, Zimmerman PV. Survival of patients with biopsy-proven usual interstitial pneumonia and nonspecific interstitial pneumonia. Eur Respir J. 2002;19:1114-8.

Downloads

Published

2017-01-17

How to Cite

Vij, A. S., Shah, M. Y., Singh, N., Sharma, S. K., & Singh, A. (2017). Nonspecific interstitial pneumonia presenting with high grade fever: a case report. International Journal of Research in Medical Sciences, 3(12), 3882–3884. https://doi.org/10.18203/2320-6012.ijrms20151461

Issue

Section

Case Reports