Effect of diet control and exercise on the lipid profile of obese men
Keywords:
Obesity, Abnormal lipid profile, Treadmill exerciseAbstract
Background: Obesity is a major health problem which might contribute to many other problems such as heart disease and hypertension as well as diabetes due to abnormal lipid profile. The main objective of the current study was to compare the effectiveness of diet or treadmill exercise on normalizing the lipid profile of obese subjects.
Methods: Forty women complaining from obesity was enrolled in this study and was randomly divided into 4 groups: control group: 10 obese women which don’t receive any thing, diet group: 10 obese women which received polysaturated fatty acid diet, exercise group: 10 obese women which received treadmill exercise for 30 minutes and lastly diet/exercise group: 10 obese women which received both diet and exercise. Measurement of weight, body mass index, and lipid profile for all groups was measured before and after 60 days of treatment intervention.
Results: Diet and exercise should have a highly significant decrease of weight and body mass index and normalizing the lipid profile (p≤0.05) under the current situation used in this study.
Conclusions: It was concluded that the combination of diet and exercise was highly effective in normalizing the lipid profile and overcoming obesity.
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References
Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM. Prevalence of overweight and obesity in the United States, 1999-2004. JAMA: the journal of the American Medical Association 2006;295:1549-55.
Gortmaker SL, Must A, Perrin JM, Sobol AM, Dietz WH. Social and economic consequences of overweight in adolescence and young adulthood. The New England journal of medicine 1993;329:1008-12.
Mokdad AH, Ford ES, Bowman BA, Dietz WH, Vinicor F, Bales VS, Marks JS. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA: the journal of the American Medical Association 2003;289:76-9.
Must A, Spadano J, Coakley EH, Field AE, Colditz G, Dietz WH. The disease burden associated with overweight and obesity. JAMA: the journal of the American Medical Association 1999;282:1523-9.
Lalonde L, Gray-Donald K, Lowensteyn I, Marchand S, Dorais M, Michaels G, Llewellyn-Thomas HA, O’Connor A, Grover SA. Comparing the benefits of diet and exercise in the treatment of dyslipidemia. Preventive medicine 2002;35:16-24.
Neter JE, Stam BE, Kok FJ, Grobbee DE, Geleijnse JM. Influence of weight reduction on blood pressure: a meta-analysis of randomized controlled trials. Hypertension 2003;42:878-84.
Dattilo AM, Kris-Etherton PM. Effects of weight reduction on blood lipids and lipoproteins: a meta-analysis. The American journal of clinical nutrition 1992;56:320-8.
Wadden TA, Anderson DA, Foster GD. Two-year changes in lipids and lipoproteins associated with the maintenance of a 5% to 10% reduction in initial weight: some findings and some questions. Obesity research 1999;7:170-8.
Fernandez ML, Metghalchi S, Vega-López S, Conde-Knape K, Lohman TG, Cordero-Macintyre ZR. Beneficial effects of weight loss on plasma apolipoproteins in postmenopausal women. The Journal of nutritional biochemistry 2004;15:717-21.
Ditschuneit HH, Flechtner-Mors M, Johnson TD, Adler G. Metabolic and weight-loss effects of a long-term dietary intervention in obese patients. The American journal of clinical nutrition 1999;69:198-204.
Heilbronn LK, Noakes M, Clifton PM. Energy restriction and weight loss on very-low-fat diets reduce C-reactive protein concentrations in obese, healthy women. Arteriosclerosis, thrombosis, and vascular biology 2001;21:968-70.
Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. The New England journal of medicine 2000;342:836-43.
Dufaux B, Schmitz G, Assmann G, Hollmann W. Plasma lipoproteins and physical activity. International journal of sports medicine 1982;3(Suppl 1):58-60.
Herbert PN, Bernier DN, Cullinane EM, Edelstein L, Kantor MA, Thompson PD. High-density lipoprotein metabolism in runners and sedentary men. JAMA: the journal of the American Medical Association 1984;252:1034-7.
Slater PE, Kark JD, Friedlander Y, Kaufmann NA, Eisenberg S, Stein Y. Reported physical activity and blood lipids in Jerusalem adults. Israel journal of medical sciences 1982;18:1144-9.
Goh VHH, Tain CF, Tong TYY, Mok HPP, Wong MT. Are BMI and other anthropometric measures appropriate as indices for obesity? A study in an Asian population. Journal of lipid research 2004;45:1892-8.
McGowan NW, Artiss JD, Strantberg DR ZBA. A peroxidase-coupled method for the colorimetric determination of serum triglycerides. Clin Chem 1983;29:583.
Richmond W. Preparation and properties of a cholesterol oxidase from Nocardia sp. and its application to the enzymatic assay of total cholesterol in serum. Clinical chemistry 1973;19:1350-6.
Finley PR, Schifman RB, Williams RJ, Lichti DA. Cholesterol in high-density lipoprotein: use of Mg2+/dextran sulfate in its enzymic measurement. Clinical chemistry 1978;24:931-3.
Kostner GM. Letter: Enzymatic determination of cholesterol in high-density lipoprotein fractions prepared by polyanion precipitation. Clinical chemistry 1976;22:695.
Castelli WP, Doyle JT, Gordon T, Hames CG, Hjortland MC, Hulley SB, Kagan A, Zukel WJ. HDL cholesterol and other lipids in coronary heart disease. The cooperative lipoprotein phenotyping study. Circulation 1977;55:767-72.
Roberts WC. The Friedewald-Levy-Fredrickson formula for calculating low-density lipoprotein cholesterol, the basis for lipid-lowering therapy. The American journal of cardiology 1988;62:345-6.
Hubert HB, Feinleib M, McNamara PM, Castelli WP. Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study. Circulation 1983;67:968-77.
Beegom R, Beegom R, Niaz MA, Singh RB. Diet, central obesity and prevalence of hypertension in the urban population of south India. International journal of cardiology 1995;51:183-91.
Buchowski MS, Sun M. Energy expenditure, television viewing and obesity. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1996;20:236-44.
Haskell WL, Leon AS, Caspersen CJ, Froelicher VF, Hagberg JM, Harlan W, Holloszy JO, Regensteiner JG, Thompson PD, Washburn RA. Cardiovascular benefits and assessment of physical activity and physical fitness in adults. Medicine and science in sports and exercise 1992;24:S201-20.
Sucić M, Oresković I. Effect of kinesiologic recreation on plasma lipoproteins and apolipoproteins in fertile women. Metabolism: clinical and experimental 1995;44:701-4.
Hartung GH, Lawrence SJ, Reeves RS, Foreyt JP. Effect of alcohol and exercise on postprandial lipemia and triglyceride clearance in men. Atherosclerosis 1993;100:33-40.
Oyelola OO, Rufai MA: Plasma lipid, lipoprotein and apolipoprotein profiles in Nigerian university athletes and non-athletes. British journal of sports medicine 1993, 27:271–4.
Moreno JJ, Mitjavila MT. The degree of unsaturation of dietary fatty acids and the development of atherosclerosis (review). The Journal of nutritional biochemistry 2003;14:182-95.
Chang NW, Huang PC. Comparative effects of polyunsaturated- to saturated fatty acid ratio versus polyunsaturated- and monounsaturated fatty acids to saturated fatty acid ratio on lipid metabolism in rats. Atherosclerosis 1999;142:185-91.
