Rasmussen’s encephalitis in an Indian child

Pokhraj P. Suthar, Shreyans M. Doshi, Prakash J. Rana

Abstract


A 5 year old boy with history of recurrent seizures and progressive weakness in left upper & lower limb. On MRI scan atrophy of right cerebral hemisphere with prominent right sided sulci & sylvian fissure. Temporal horn of right lateral ventricle appears prominent. Body and genu of corpus callosum appears hypo plastic. Electroencephalography revealed moderate voltage record showing mixed activity comprising ill-defined 8-10 Hz alpha rhythm plus 4-7Hz waves and random background delta components at 3Hz frequency. A clinical diagnosis of focal tonic-clonic epilepsy was made secondary to Rasmussen’s encephalitis, based on the features MRI scan findings of the brain.


Keywords


Paediatrics, Central nervous system, MRI

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References


Honavar M, Janota I, Polkey CE. Rasmussen’s encephalitis insurgery for epilepsy. Dev Med Child Neurol. 1992;34:3-14.

Rassner Michael P, van Velthoven-Wurster Vera, Ramantani Georgia, Feuerstein Thomas J. (Altered transporter-mediated neocortical GABA release in Rasmussen’s encephalitis. Epilepsia. 2013 Mar;54(3):e41-4.

Bien CG, Widman G, Urbach H et al. The natural history of Rasmussen’s encephalitis. Brain. 2002;125:1751-9.

Rogers SW, Andrews PI, Gahring LC et al. Autoantibodies to glutamate receptor GluR3 in Rasmussen’s encephalitis. Sci. 1994;265:648-51.

Fokuda T, Oguni H, Vanagaki S et al. Chronic Localised encephalitis preceded by Ipsilateral uveitis: a case report. Epilepsia. 1994;35:1328-31.

Chiapparini L, Granata T, Farina L, Ciceri E, Erbetta A, Ragona F, Freri E, Fusco L, Gobbi G, Capovilla G, Tassi L, Giordano L, Viri M, Dalla Bernardina B, Spreafico R, Savoiardo M. Diagnostic imaging in 13 cases of Rasmussen’s encephalitis: can early MRI suggest the diagnosis? Neuroradiol. 2003;45(3):171-83.

Osborne AG. Rasmussen’s encephalitis. In: Osborne AG, Blaser SI, Salzman KL, Katzman GL, Provenzale J, Castillo M, Hedlund GL, Illner A, Harnsberger HR, Cooper JA, Jones BV, Hamilton BE, eds. Diagnostic Imaging Brain. 1st ed. Utah: Amirsys Inc; 2005: 42-45.

Burneo JG, Hamilton M, Vezina W, Parrent A. Utility of Ictal SPECT in the presurgical evaluation of Rasmussen’s encephalitis. Can J Neurol Sci. 2006;33(1):107-10.

Ramesha KN, Rajesh B, Ashalatha R, Kesavadas C, Abraham M, Radhakrishnan VV, Sarma PS, Radhakrishnan K. Rasmussen’s encephalitis: experience from a developing country based on a group of medically and surgically treated patients. Seizure. 2009;18(8):567-72.