DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20170161

Effects of different phases of menstrual cycle on lung functions in young girls of 18-24 years age

Manish Goyal, S. K. Dwivedi, Ajit Singh Rajput

Abstract


Background: The dynamic cyclical changes in the levels of various hormones during different phases of menstrual cycle are known to affect functioning of different systems of the body, including the respiratory system. Objective of the study was to study the effects of different phases of menstrual cycle on lung functions in young girls of 18-24 years age.

Methods: 78 girls who were medical students of G.R. Medical College, Gwalior, India were chosen for the study. Their lung function parameters were recorded on Spiro Excel, a computerized spirometer. Four lung function parameters i.e. FVC, FEV1, FEV1/FVC% and PEFR were recorded in the different phases of menstrual cycle i.e. menstrual phase, proliferative phase and secretory phase.

Results: All lung function parameters except FEV1/FVC% were least in menstrual phase and highest in secretory phase with in between values in proliferative phase. The values were significantly different among the three phases. FEV1/FVC% values were maximum in menstrual phase, lowest in secretory phase with intermediate values in proliferative phase but the values were not significantly different among the three phases. Mean values of FVC, FEV1 and PEFR were higher in all the phases of menstrual cycle in normal BMI subjects as compared to the corresponding phases of underweight subjects.

Conclusions: Higher values of lung functions during proliferative and secretory phases can be attributed to the higher concentrations of sex hormones specially progesterone because in most of the studies progesterone is known to cause relaxation of bronchial smooth muscle.

Keywords


Lung function, Menstrual cycle, Young girls

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References


Guyton AC, Hall JE. Female physiology before pregnancy and female hormones. In: Textbook of medical physiology. 11th ed. Philadelphia: Elsevier. 2006;1011-26.

Real FG, Svanes C, Omenaas ER, Antò JM, Plana E, Jarvis D, et al. Lung function, respiratory symptoms and the menopausal transition. J Allergy Clin Immunol. 2008;121:72-80.

Nandhini R, Subhashini AS. Variation in the pulmonary functions with the phases of the menstrual cycle in adolescent females. J Clin Diagnost Res. 2012;6(2):173-5.

Dabhoiwala S, Kathrotia R, Patel D. Pulmonary functions in different phases of menstrual cycle and its relation with serum progesterone levels. National J Integrated Res Med. 2011;2(4):39-42.

Shah HD, Shaikh WA, Patel D, Singh SK. Dynamic lung functions in underweight Gujrati Indian adolescent boys. National J Community Med. 2012;3(1):142-5.

Ghobain MA. The effect of obesity on spirometry tests among healthy non-smoking adults. BMC Pulm Med. 2012;12:10.

Jeon YH, Yang HJ, Pyun BY. Lung function in Korean adolescent girls: in association with obesity and the menstrual cycle. J Korean Med Sci. 2009;24:20-25.

Kannan N, Kumar RA, Ramaprabha P. Evaluation of haematological and pulmonary function test parameters in different phases of menstrual cycle in rural south Indian population, Int J Bioiassays. 2013;2(3):506-9.

Bidikar MP, Maskeri D. Pulmonary function tests in different phases of menstrual cycle. Global Res Analysis. 2013;2(7):136-7.

Gavali MY, Gavali YV, Gadkari JV, Patil KB. Influence of menstrual cycle on lung functions in young healthy medical students. Int J Healthcare Biomed Res. 2013;2(1):30-4.

Pai SR, Prajna P, D'Souza UJA. A correlative study on blood pressure and lung function profiles during different phases of menstrual cycle among Indian population. Thai J Physi Sci. 2004;17(2):30-4.

Park K. Obesity. In: Park's Textbook of Preventive and Social medicine. 21st ed. Jabalpur: Banarsidas Bhanot Publishers. 2011;366-70.

Arora D, Kaur P, Arora M, Gupta U. Influence of menstrual cycle on lung functions in asthmatic females. Indian J Fundamental Applied Life Sci. 2011;1(4):62-7.

Hebbar KR. Comparative Study of pulmonary function tests in women in different phases of menstrual cycle with and without contraceptive pills. IOSR J Dental Med Sci. 2013;8(5):21-5.

Da Silva SB, Viana EDSR, De Sousa MB. Changes in peak expiratory flow and respiratory strength during the menstrual cycle. Respir Physiol Neurobiol. 2006;150:211-9.

Das TK. Effects of the menstrual cycle on timing and depth of breathing at rest. Indian J Physiol Pharmacol.1998;42(4):498-502.

Chong E, Ensom MHH. Peak expiratory flow rate and premenstrual symptoms in healthy non asthmatic women. Pharmacotherapy. 2000;20(12):1409-16.

Satyanarayana P, Roy M, Parmar C. Assessment of Lung functions in obese young adolescent medical students. IOSR J Dental Med Sci. 2014;13(5):17-20.