A rare case report of primary renal squamous cell carcinoma

Sneha P. Chavarkar, Amit K. Agrawal, Alok C. Shrivastava, Anuradha V. Shrikhande


Primary renal squamous cell carcinoma is a very rare entity. Only few cases are reported in the world literature. Most of the patients present at a late stage resulting in poor prognosis. We report a 44 year old female who presented with a history of lump in right flank accompanied with a dull intermittent pain for 2 months duration which intensified in the last 15 days. Antecedent risk factors like renal calculi, analgesic use were absent. Computed Tomography (CT) examination revealed a mass arising from the superior pole of kidney with extension to the posterior segment of liver. Histopathology following nephrectomy showed histological features of well differentiated squamous cell carcinoma.


Carcinoma, Renal, Squamous

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Pahwa M, Pahwa AR, Girotra M, Chawla A. Atypical presentation of primary renal squamous cell cancer: a case report. Int J Cancer Ther Oncol. 2014;2(1):2015.

Bandopadhyay R, Biswas S, Nag D, Ghosh AK. Squamous cell carcinoma of the renal pelvis presenting as hydronephrosis. J Can Res Ther. 2010;6:537-9.

Li MK, Cheung WL. Squamous cell carcinoma of the renal pelvis. J Urol. 1987;138:269-71.

Lee TY, Ko SF, Wan YL, Cheng YF, Yang BY, Huang DL, et al, Renal Squamous cell carcinoma: CT findinds and clinical significance. Abdom Imaging. 1998;23:203-8.

Holmang S, Lele SM, Johansson SL. Squamous cell carcinoma of the renal pelvis and ureter: incidence, symptoms, treatment and outcome. J Urol. 2007;178:51-6.

Karabulut A, Emir L, Gonultas NI. Squamous cell carcinoma located in the renal caliceal system: A case report and review of the literature. Turkish J of Cancer. 2002;32:20-4.