Seronegative celiac disease: a case report

Amita Surana, Vaishali Chaudhari, Shefali Patel


In this article we report a case of 17 years old male with short stature, severe anaemia and delayed puberty. After extensive workup and in-spite of being seronegative for celiac antibodies, he was diagnosed as an atypical case of celiac disease based on duodenal biopsy report suggestive of CD. The patient is put on gluten free diet along with other nutritional supplements. Long term consequences like short stature, infertility can be prevented by higher clinical suspicion and early diagnosis. Intestinal biopsy should be performed if there is strong clinical suspicion. The relevant literature has been reviewed and discussed in brief.


Celiac disease, Delayed puberty, Intestinal biopsy, Serology

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