Development and histogenesis of human foetal lung in relation with gestational age

K. Satheesh Naik, K. Madhavi, M. Gurushanthaiah, G. M. Mahesh

Abstract


Background:The objective was to study the development and histogenesis of human foetal lung in relation with different gestational age.

Methods:In the present study lung specimens were collected from formalin fixed 27 aborted foetuses (14 male, 13 female) by abdominal dissection between 6 weeks to 40 weeks of gestational age.

Results:In the present study we observed that there was a delay in the appearance of embryonic, pseudo glandular phase, canalicular, terminal saccular and alveolar stages of the lung.

Conclusion:Delay in the developmental anatomy and histogenesis of the lung cells leads to histopathological abnormalities which gives knowledge to the clinicians during clinical procedures.


Keywords


Embryonic, Pseudo glandular phase, Canalicular, Terminal saccular and alveolar stages

Full Text:

PDF

References


Peter Williams. Respiratory system. In: Lawrence H. Bannister, eds. Gary’s Text Book of Human Anatomy. 35th ed. Edinburgh: Churchill Livingstone; 1995: 1821-1865.

Keith L. Moor, T. V. N. Persaud. Respiratory system. In: Keith L. Moor, T. V. N. Persaud, eds. The Developing Clinical Oriented Embryology. 6th ed. Philadelphia: Saunders; 1999: 242-251.

Micheal H. Ross, Lynn J. Romrell, Gordon I. Kaye. Bronchi. In: Micheal H. Ross, Lynn J. Romrell, Gordon I. Kaye, eds. Histology Text Book and Atlas. 3rd ed. Philadelphia: Williams & Wilkins; 1995: 530- 547.

Ajmani ML. Practical embalming. In: Ajmani ML, eds. Text Book Principles of Embalming Techniques in Autopsied Body. 1st ed. New Delhi: Jaypee Brothers Publishers; 1993: 131-134.

Mossman Boyd, Hamilton. Development of respiratory system. In: William James Hamilton, James Dixon Boyd, Harland Winfield Mossman, eds. Human Embryology (Prenatal Development of Formation and Function). 3rd ed. Cambridge: Heffer; 1964: 230-234.

Inderbir Singh. Respiratory system. In: Inderbir Singh, eds. Human Embryology. 7th ed. New Delhi: Jaypee Brothers Publishers; 2003: 199-202.

A. K. Datta. Lung. In: A. K. Datta, eds. Essentials of Human Embryology. Kolkata, India: Current Distributors; 5th ed. 2005: 155-157.

Bruce M. Carlson. The developing human lung. In: Bruce M. Carlson, eds. Human Embryology and Developmental Biology. 1st ed. St. Louis: Mosby; 1959: 341-342.

Mednet. Lung, 2014. Available at: Mednet.Co.Kr/Anatomy/Embryology/m-Thorax Y.20 Lung. Htm-22K.

Thomas W. Sadler. Lungs and gut. In: Thomas W. Sadler, Jan Langman, eds. Longman’s Medical Embryology. 6th ed. Philadelphia: Lippincott Williams & Wilkins; 1999: 275-284.

John D. Bancroft. Fixation of tissues. In: John D. Bancroft, Marilyn Gamble, eds. Theory and Practical of Histological Techniques. 5th ed. US: Elsevier Health Sciences; 2002: 155-156.

Surventa. Lung, 2014. Available at: www.surventa.com/htm/general information/babysneed.com.