Indian common krait envenomation presenting as fulminant myocarditis and coma: a case report

Vijay Kumar Verma, Vijender Maurya, Rajesh Verma

Abstract


Fulminant myocarditis is an unusual manifestation of cardiotoxicity with severe elapid snake envenoming and is meagrely reported with snake bite due to Indian common krait. We report a 12-year-old boy who was admitted in complete locked-in state and hemodynamic instability after severe neurotoxic snake envenoming by Bungarus caeruleus (Indian common krait). His hospital course was complicated with recurrent episodes of sustained ventricular tachycardia requiring defibrillation; and cardiogenic shock requiring inotropes, vasopressors and intraaortic balloon counterpulsation. Severe heart failure features secondary to fulminant toxic myocarditis persisted even after full neurological recovery requiring prolonged standard medical heart failure therapy. Patient subsequently achieved full clinical recovery and regained normal left ventricular systolic function. We also reviewed the literature on cardiac manifestations, possible mechanisms and treatment of patients with cardiotoxicity due to elapid snake bites. The importance of anticipating severe cardiovascular complications is highlighted to help formulate appropriate therapeutic strategy.


Keywords


Bungarus caeruleus, Cardiotoxicity, Cardiogenic shock, Envenoming, Fulminant myocarditis, Heart failure, Indian common krait, Neurotoxicity, Neuroparalysis, Ophthalmoplegia, Snake antivenin

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References


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