Ocular involvement in diabetic patients attending tertiary care centres of eastern U.P., India: a prospective study

Nutan Saxena, A. M. Jain, Perwez Khan, Ruchika Agarwal, Harish Chandra Tiwari, Anita Thakur

Abstract


Background: Diabetes mellitus is increasing day by day in developing countries especially in India. It is a main treatable cause of morbidity in eye. Diabetic cataract, neovascular glaucoma and retinopathy are important ocular complications due to diabetes mellitus. The objective was to study the variations in ocular complications in patients of diabetes mellitus.

Methods: A prospective study from July 2012 to June 2013 was conducted in RMCH and RC, Kanpur & GSVM Medical College, Kanpur. One hundred one selected diabetic patients who are having abnormal slit lamp and fundus examination were included in this study.

Results: In our study it was found that more the duration of diabetes, greater the severity of diabetes. Well controlled diabetics have lesser complications in eyes due to diabetes.

Conclusion: Patient’s age, sex, duration and control of diabetes play important role in development and severity of complications in eye due to diabetes mellitus.


Keywords


Diabetes mellitus, Cataract, Neovascular glaucoma, Retinopathy, Haemorrhage

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References


Moy CS. Diabetes 1991 vital statistics. Alexandria VA: American diabetis association; 1991.pg 13.

Wild S, Roglic G, Green A, Sicree R, King, H. Global prevalence of Diabetes. pg - 1047-53.

Klein R. Retinopathy in a population based study. Trans American Ophthalmol. Society 1992; 90: pg -561-94.

J. H. Kinoshita, “Mechanisms initiating cataract formation. Proctor lecture,” Investigative Ophthalmology, vol. 13, no. 10, pp. 713–724, 1974.

J. H. Kinoshita, S. Fukushi, P. Kador, and L. O. Merola, “Aldose reductase in diabetic complications of the eye,” Metabolism, vol. 28, no. 4, pp. 462–469, 1979.

J. L. Goldstein, “How a jolt and a bolt in a dentist's chair revolutionized cataract surgery,” Nature Medicine, vol. 10, no. 10, pp. 1032–1033, 2004.

Ritch, R., Shields MB, Krupin T, The Glaucomas, St. Louis, MO: Mosby; 1989:1067.

Striga, M. et al. Ophthalmologica 1993; 207:144–147.

Jacobson DR, Murphy RP, Rosenthal AR: The treatment of angle neovascularization with panretinal photocoagulation. Ophthalmology 86: 1270–1277, 1979.

Zeiter J H, Shin DH, Baek NH: Visual field defects in diabetic patients with Primary Open angle glaucoma.Am. J Ophthal 111:581-584, 1991.

Pardianto G et al. (2005). "Understanding diabetic retinopathy". Mimbar Ilmiah Oftalmologi Indonesia 2: 65-6.

Congdon NG, Friedman DS, Lietman T: Important causes of visual impairment in the world today. JAMA 290:2057–2060, 2003.

P.-J. Guillausseau, P. Massin, M.-A. Charles, et al., “Glycaemic control and development of retinopathy in type 2 diabetes mellitus: a longitudinal study,” Diabetic Medicine, vol. 15, no. 2, pp. 151–155, 1998.

R. Turner, “Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33),”The Lancet, vol. 352, no. 9131, pp. 837–853, 1998.

Negahban K, Chern K: Cataracts associated with systemic disorders and syndromes. Curr Opin Ophthalmol 13:419-422, 2002.

Pirie A: Epidemiological and biochemical studies

of cataract and diabetes. Invest Ophthalmol 4:629–637, 1965.

Mohamed Q, Gillies MC, Wong TY: Management of diabetic retinopathy: a systematic review. JAMA 298:902–916, 2007.