Study of biochemical markers in iron deficiency anemia

Authors

  • Smita A. Deokar Department of Biochemistry, LTMMC and LTMGH, Sion, Mumbai
  • Pooja S. K. Rai Department of Biochemistry, LTMMC and LTMGH, Sion, Mumbai
  • Amruta A. Bakshi Department of Biochemistry, Terna Medical College and Hospital, Mumbai
  • Anita B. Rai Department of Microbiology, B.N. Bandodkar College of Science, Thane

Keywords:

Oxidants, Antioxidants, IDA (Iron Deficiency Anemia)

Abstract

Background: The present study was aimed to study alterations in levels of oxidants and antioxidants in iron deficiency anemia (IDA).

Methods: 30 patients of IDA in age group of 20-50 and 30 healthy subjects were included for study. Serum Iron, TIBC & Hb% were estimated to diagnose IDA. Serum Malondialdehyde (MDA), Nitric oxide (NO) as an oxidants & Superoxide dismutase (SOD), vitamin E, vitamin C, Zinc (Zn) levels as antioxidants were estimated.

Results: Significant decreased levels of Hb%, serum iron, SOD, Vitamin C, vitamin E, Zn were found. TIBC, MDA, NO were significantly increased as compared to controls.

Conclusion: The normal adult erythrocytes can resist oxidative stress by several antioxidant defense systems. In IDA, oxidative stress causes lipid peroxidation and membrane damage. So antioxidants can be used as a marker for prevention of membrane damage due to oxidative stress.

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Published

2017-01-28

How to Cite

Deokar, S. A., Rai, P. S. K., Bakshi, A. A., & Rai, A. B. (2017). Study of biochemical markers in iron deficiency anemia. International Journal of Research in Medical Sciences, 1(4), 541–544. Retrieved from https://www.msjonline.org/index.php/ijrms/article/view/2662

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Original Research Articles