Prevalence of hepatitis B and C among patients admitted in respiratory medicine ward of a tertiary care hospital in Mullana, Ambala, Haryana, India

Ankit Sharma; Sameer Singhal; Dinesh Mehta; Abinav Dagar

doi:10.18203/2320-6012.ijrms20171262

Authors

Ankit Sharma Department of Respiratory Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India
Sameer Singhal Department of Respiratory Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India
Dinesh Mehta Department of Respiratory Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India
Abinav Dagar Department of Respiratory Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20171262

Keywords:

Hepatitis, Prevalence, Unsafe therapeutic injections

Abstract

Background: Viral Hepatitis B and C have become a major public health problem. Hepatitis B affects approximately 30% of world population or about 2 billion people have serological evidence of either current or past infection. Hepatitis C virus infects approximately 3% of world population placing about 170 million people at risk of liver disease. In India, HBsAg prevalence rates among general population ranges from 0.1% to 11.7%, being 2% to 8% in most studies and seroprevalence for Hepatitis C ranges from 0.1% to 8% among general population.

Methods: The study was conducted in the respiratory medicine Ward, MMIMSR in the month of August 2016. 200 patients were taken up for the study after clinical examination, necessary investigation and proper consent. Patients were tested for HBsAg antigen and HCV Tridot. Patients were put through a carefully designed questionnaire to look for possible cause of infection. Patients who came out to be positive for either Hepatitis B or C were counselled about further investigations and treatment options.

Results: The prevalence rate for Hepatitis B came out to be 9% and for Hepatitis C was 5.5%. Hepatitis has become a major public health issue in India particularly in the rural areas. High prevalence rates among patients with respiratory diseases can be attributed to unsafe therapeutic injections and use of shared needles.

Conclusions: There is a need to carry out larger studies to better elucidate the epidemiology of Hepatitis B and C and to identify high prevalence areas and simultaneously focus on improving public health measures to prevent disease transmission and decrease the burden of disease.

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Author Biography

Ankit Sharma, Department of Respiratory Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India

PG RESIDENT, DEPARTMENT OF RESPIRATORY MEDICINE

References

Hou J, Liu Z, Gu F. Epidemiology and Prevention of Hepatitis B Virus Infection. Inter J Med Scie. 2005;2(1):50-7.

WHO. Global surveillance and control of hepatitis C. Report of a WHO Consultation organized in collaboration with the Viral Hepatitis Prevention Board, Antwerp, Belgium. J Viral Hepat. 1999;6:35-47.

Acharya SK, Panda SK, Duphare H. Chronic hepatitis in a large Indian hospital. Natl Med J India. 1993;6:202-6.

Panigrahi AK, Panda SK, Dixit RK, Rao KV, Acharya SK, Dasarathy S, et al. Magnitude of hepatitis C virus infection in India: prevalence in healthy blood donors, acute and chronic liver diseases. J Medical Viro. 1997;51(3):167-74.

Shepard CW, Simard EP, Finelli L, Fiore AE, Bell BP. Hepatitis B virus infection: epidemiology and vaccination. Epidemiol Reviews. 2006;28(1):112-25.

Chowdhury A, Santra A, Chaudhuri S, Ghosh A, Banerjee P, Mazumder DN. Prevalence of hepatitis B infection in the general population: a rural community based study. Trop gastroenterol J Digest Dis Found. 1998;20(2):75-7.

Suzuki H, Woodfield G. Viral hepatitis in Asia: summary of a plenary session. In Viral Hepatitis and Liver Disease. 1994:385-6.

Uppal Y, Garg S, Malhotra S, Singh MM, Gupta VK, Mishra B, et al. Hepatitis B and C virus infection in an urban slum of Northern India. J Commun Dis. 2009;41(3):201-4.

Chowdhury A, Santra A, Chaudhuri S, Dhali GK, Chaudhuri S, Maity SG, et al. Hepatitis C virus infection in the general population: A community‐based study in West Bengal, India. Hepatol. 2003;37(4):802-9.

Bharadwaj BV, Vazhavandal G, Uma A. Seroprevalence of hepatitis C virus Infection among patients attending a rural teaching hospital in South India: a three year study. Int J Curr Microbiol App Sci. 2014;3(2):123-7.

Sood A, Sarin SK, Midha V, Hissar S, Sood N, Bansal P, et al. Prevalence of hepatitis C virus in a selected geographical area of Northen India: A population based survey. Indian J Gastroenterol. 2012;31(5):232-6.

Kane A, Lloyd J, Zaffran M, Simonsen L, Kane M. Transmission of hepatitis B, hepatitis C and human immunodeficiency viruses through unsafe injections in the developing world: model-based regional estimates. Bulletin of the World Health Organization. 1999;77(10):801-7.

Singh J, Gupta S, Khare S, Bhatia R, Jain DC, Sokhey J. A severe and explosive outbreak of hepatitis B in a rural population in Sirsa district, Haryana, India: unnecessary therapeutic injections were a major risk factor. Epidemiol Infect. 2000;125(03):693-9.