An unusual presentation of hemoglobin SD Punjab in a Saudi Arabian adult

Soheir S. Adam; Ahmed N. Sahly; Ahmed A. Jamjoom; Abdulrahman H. Ghoneim; Thunayyan M. Almasoudi; Mohammed O. Mohsen; Maha A. Badawi

doi:10.18203/2320-6012.ijrms20170934

Authors

Soheir S. Adam Department of Hematology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
Ahmed N. Sahly Department of Hematology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
Ahmed A. Jamjoom Department of Hematology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
Abdulrahman H. Ghoneim Department of Hematology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
Thunayyan M. Almasoudi Department of Hematology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
Mohammed O. Mohsen Department of Hematology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
Maha A. Badawi Department of Hematology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia http://orcid.org/0000-0003-3272-2393

DOI:

https://doi.org/10.18203/2320-6012.ijrms20170934

Keywords:

Hemoglobin D, Sickle cell anemia

Abstract

HbDPunjab is an uncommon variant hemoglobin that does not result in significant pathology when inherited as a homozygous disorder. When inherited with other hemoglobinopathies, it may result in varying disease phenotypes. HbSDPunjab has been rarely reported in Saudi Arabia, coexisting with alpha or beta thalassemia. In this report, we discuss the case of a 39 years old male who presented with severe anemia and renal injury and was later diagnosed with HbSDPunjab through electropheresis and genetic testing.

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