DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20171852

Histopathological spectrum of ovarian tumours from a referral hospital in Kashmir valley, Jammu and Kashmir, India

Sheema Sheikh, Humaira Bashir, Summyia Farooq, Arshi Beigh, Farzana Manzoor, Ruby Reshi

Abstract


Background: Ovary is a complex structure and its neoplasms show a wide spectrum of histological types and clinical behaviour. The present study was done with the aim of studying the histopathological pattern of the ovarian tumours in women of various age groups.

Methods: This was prospective study conducted over a period of 2 years from Jan 2015 to Dec 2016 and included 193 cases of ovarian neoplasms.

Results: Of 193 cases 155 (80.3%) were benign, 8 (4.1%) were borderline and 30 (15.5%) were malignant tumours. Surface epithelial tumours constituted majority of the tumours (64.7%). Mature cystic teratoma (30.6%%) was the most common benign tumour followed by serous cyst adenoma (26.9%). Serous cyst adenocarcinoma (7.8%) was the most common malignant tumour of the ovary. While tumours were seen over a wide range of 6-75 years, >80% of benign tumours were seen in patients of <40 years and 60% of malignant tumours were seen in patients of >40 years of age.

Conclusions: The findings of present study are comparable to the published data from the subcontinent.


Keywords


Mature cystic teratoma, Ovarian tumors, Surface epithelial

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References


Tavassoli FA, Devilee P. Classification of Tumours. Pathology and Genetics of Tumours Of the Breast and Female Genital Organs. IARC Press. 2003.

Tortolero L, Mictchell FM, Rhodes HE. Epidemiology and screening of ovarian cancer. Obstet Gynecol Clin North Am. 1994;21:63-75.

Murthy NS, Shalini S, Suman G, Pruthvish S, Mathew A. Changing trends in incidence of ovarian cancer- the Indian scenario. Asian Pac J cancer prev. 2009;10(6):1025-30.

Rasool MT, Lone MM, wani ML, Afroz F, Zaffar S, Mohib-ul-Haq M. Cancer in Kashmir, India; burden & pattern of diseases. J Cancer Res Ther. 2012;8:243-6.

Day NE, Krishnan E. Epidemiology of gynaecological cancers. Gynaecology by Shaw R W. 2nd ed. Edinburgh: Churchill Living Stone, 1997;477-87.

Ellenson LH, Edyta C and Pirog. The female genital tract. Robbins and Cotran Pathologic Basis of Disease. 8th edition., Elsevier, A division of Reed Elsevier India Pvt. Ltd. 2010;22:1005-63.

Saxena MHK, Devi G, Prakash P, Pantrajan P. Ovarian neoplasms-A retrospective study of 356 cases. J Obstret Fynec India. 1980;30:522-7.

Pilli GS, Suneeta KP, Dhaded AV, Yenni W. Ovarian tumours. A study of 282 cases. J Indian Med Assoc. 2002;100:420,423-24,447.

Prabhakar BR, Maingi K. Ovarian tumours-Prevalence in Punjab. Indian J Pathol Microbiol. 1989;32:276-81.

Gupta N, Bisht D, Agarwal AK, Sharma VK. Retrospective and prospective study of ovarian tumours and tumour like lesions. Indian J Pathol Microbiol. 2007;50:525-7.

Bukhari U, Memon Q, Memon H. Frequency and pattern of ovarian tumours. Pak J Med Sci. 2011;27:884-6.

Gupta GC, Singh PA, Mehrotra TN, Agarwal R: A clinicopathological study of ovarian tumours. Indian J Pathol Microbiol. 1986;29:354-62

Maheshwari V, Tyagi SP, Saxena K, Tyagi N, Sharma R, Aziz M, Hameed F. Surface epithelial tumours of the ovary. Indian J Pathol Microbiol. 1994;37:75-85.

Momtahen S, Kadivar M, Kazzazi AS, Gholipour F et al: Gynaecologic malignancies in Tehran. Indian J of Cancer. 2009;46:226-30.

Thanikasalam K, Ho CM, Adeeb N. Pattern of ovarian tumour among Malaysian women at General Hospital, Kuala Lumpur. Med J Malayasia. 1992:47:139-46

Vadiya S, Sharma P, KC S, Vadiya SA. Spectrum of ovarian tumours in a referral hospital in Nepal. J Pathol of Nepal. 2014;4:539-43.

Jha R, Karki S. Histological pattern of ovarian tumors and their age distribution. Nepal Med Coll J. 2008;10:81-5.

Amatya S, Gurung G, Rana A. Annual Clinicopathological Analysis of Ovarian tumors at TUTH. Nepal J Obstetrics and Gynaecology. 2010;4:18-24.