Published: 2017-07-26

Clinical profile of patients with cutaneous disorders

Khileshwar Singh, Kamlesh Dhruv, Amit Thakur


Background: 50-75% of all the patients who are on dialysis suffer from significant xerosis. But the exact cause is difficult to trace. Acquired ichthyosis is seen in some patients. Atrophy of sebaceous glands is seen in patients with uraemia. Such patients also show overall decrease in sweet volume. Objective was to study the clinical profile of patients with cutaneous disorders.

Methods: A hospital based prospective study was carried out from September 2012 to February 2013 at a tertiary care centre of Late Baliram Kashyap memorial government medical college, Jagdalpur, Chhattisgarh, India. A total of 50 patients with cutaneous disorders were studied with respect to their clinical profile. Patients not willing to participate in the present study as per the protocol were excluded from the study. But patients giving their willingness to participate in the present study as per the protocol of the study were included in the study.

Results: The males constituted 58% of the total cases and the females constituted 42% of the total cases. Maximum patients were seen in the fourth and fifth decade of their life i.e. 24% followed by the age group of 31-40 years i.e. 22%. The most common cutaneous manifestation was pruritus in 24% of cases followed by xerosis in 16% of cases. Next most common cutaneous manifestation was Tinea versicolor inn 14% of cases followed by oral candidiasis in 8% of cases and scabies were seen in 6% of cases. Both among males and females, pruritus was the most common skin lesion seen.

Conclusions: The most common cutaneous lesion found in the present study was pruritus in 24% of cases followed by xerosis (16%), Tinea versicolor (14%), oral candidiasis (8%) and scabies in 6% of cases. Cases of nail changes, herpes zoster, Tinea cruris, hyper pigmentation, folliculitis, Exfoliative dermatitis, and Kyrle’s disease, Vitiligo, Melisma and Keloid were also seems.


Clinical profile, Dialysis, Pruritus, Scabies Xerosis

Full Text:



Yosipovitch G, Hodak E, Vardi P, Shraga I, Karp M, Sprecher E, et al. The prevalence of cutaneous manifestations in IDDM patients and their association with diabetes risk factors and micro vascular complications. Diabetes Care. 1998;21(4):506-9.

Daghestani L, Pomeroy C. Renal manifestations of hepatitis C infection. Am J Med. 1999;106(3):347-54.

Muller SA, Winkelmann RK. Necrobiosis lipoidica diabeticoruum: A clinical and pathological investigation of 171 cases. Arch Dermatol. 1966;93:272.

Rosen T. Uremic pruritus: a review. Cutis. 1979;23(6):790-2.

Denman ST. A review of pruritus. J Am Acad Dermatol. 1986;14(3):375-92.

Gilchrest BA, Stern RS, Steinman TI, Brown RS, Arndt KA, Anderson WW, et al. Clinical features of pruritus among patients undergoing maintenance hemodialysis. Arch Dermatol. 1982;118(3):154-6.

Massry SG, Kopple JD. Uremic toxins: What are they? How are they identified? Semin Nephrol. 1983;3:263.

Knable AL. Cutaneous nephrology. Dermatol Clin. 2000;20:413-21.

Murphy M, Carmichael AJ. Renal itch. Clin Exp Dermatol. 2000;25(2):103-6.

Safrin S. Foscarnet therapy in five patients with AIDS and acyclovir resistant varicella zoster virus infection. Ann Intern Med. 1991;115:19.

Dawber RPR. Clinical association of vitiligo. Postgrad Med J. 1970;46:276.