Published: 2017-05-27

Prescribing trends in respiratory tract infections in a tertiary care teaching hospital

Mirza A. Beg, Shakti B. Dutta, Shalu Bawa, Amanjot Kaur, Subhash Vishal, Upendra Kumar


Background: Respiratory tract infections are a major cause of morbidity and mortality in developing countries. Polypharmacy and irrational prescribing in respiratory diseases are common practice worldwide. Keeping in consideration this scenario, present study was undertaken to analyze the drug utilization pattern of respiratory tract infections.

Methods: This drug utilization study was conducted by Pharmacology department at SGRRIM & HS to analyze drug utilization pattern of respiratory infections. A total of 585 prescriptions were collected from hospital and randomly evaluated for prescribing pattern using WHO drug indicators.

Results: A total of 585 prescriptions were analyzed. Male:Female ratio was 1:0.77. Age wise distribution was done; 81(13.84%) 0-15 years, 54(9.23%) 16-30 years, 198(33.84%) 31-45 years, 75(12.82%) 46-60 years and 177(30.25%) patients belongs to >60 years of age group respectively. A total of 4869 drugs were prescribed, 2754(56.56%) antibiotics, 675(13.8%) bronchodilators, 630(12.93%) corticosteroids, 303(6.22%) antacids, 507(10.41%) in miscellaneous category respectively. 2562(52.61%) oral, 1491(30.62%) injectable and 816(16.75%) inhalational drugs were prescribed. Numbers of Fixed dose combinations were 645(13.24%). 8.32 drugs were prescribed per prescription. 2409(49.47%) drugs were prescribed from national essential medicine list 2015. 4320(88.72%) drugs were prescribed by their brand names.

Conclusions: Irrational prescribing and polypharmacy was observed. The drug utilization studies are important tool to sensitize and increases awareness among physicians, which ultimately improves rational prescribing and patient care.


Drug utilization, Rational prescribing, Respiratory infections

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Mohan H. The Respiratory system. Text book of Pathology, 4th ed. New Delhi: Jaypee Brothers Medical Publishers (Pvt) ltd. 2000:438-9.

Prescribing of antibiotic for self-limiting respiratory tract infections in adults and children in primary care. Nice Clinical Guidelines in UK. 2008;8:69.

Khan IA, Shobha Rani RH, Subramanyam G. Efficacy and safety of azithromycin with various cephalosporins used in treatment of lower respiratory tract infection. Indian J Pharm Pract. 2009;1(2):53-61.

Gujar A, Tiwari P. Antimicrobial drug use in hospitalized children. CRIPS 2008;9(1):2-6.

Errabelly P, Ramavath V, Afreen A, Sanaboina A. Analysis of the prescribing pattern of antibiotics in respiratory tract infections at department of medicine at a tertiary care teaching hospital. IJPSR. 2015;6(7):2693-97.

Mahajan HM, Date AP, Badwaik RT, Borkar AS, Wanmali SS, Gohad GV. Analysis of pattern of antimicrobial use in RTIs in a tertiary care hospital of central india-A drug utilization study. J Cont Med A Dent. 2014;2(3):59-64.

Gogoi S, Saikia PP. A study on prescribing pattern of antibiotics for upper respiratory tract infections by general practitioners in rural areas of Assam. IJSR. 2015;4(5):60-2.

Pandit PR, Kokanii V, Bhave KA. Prescribing pattern of antimicrobials used for the treatment of acute respiratory tract infections in children. IJARSAT. 2016;18(1):171-75.

Tiwari P, Ahlawat R, Gupta G. Prescription patients of upper respiratory tract infection at a pediatric outpatient clinic in Punjab. Indian J Pharm Pract. 2014;7(2):26-32.

Mungrue K, Brown T, Hayes I Ramroop S, Thurston P, Pereira LP. Drugs in upper respiratory tract infections in pediatric patients in north Trinidad. Pharm Pract. 2009;7(1):29-33.

Gupta N, Ansari KU. Fixed dose drug combinations: their uses, regulations and future prospects. Antiseptic.1991;88:384-387.