DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20171292

Primary leiomyosarcoma in the inferior vena cava- a case report

Ravindra Kumar, Suman Chaudhary, Hemant Kumar Mishra, Divesh Goyal

Abstract


Vascular leiomyosarcoma of IVC is a rare tumor. Only about 200 cases have been reported worldwide. There is a strong predilection for females and middle segment of IVC is most commonly affected. The diagnosis is often challenging as patients present with non-specific complaints such as dyspnoea, abdominal discomfort, or back pain. A 43-year-old male presented with history of vague abdominal distention, discomfort, and dyspnoea in our hospital. Ultrasound of abdomen detected a mass in retro peritoneum with mixed echogenicity inseparable from IVC. CT Imaging examination of abdomen revealed a large elongated, heterogenous mass extending from right atrium to the confluence of common iliac veins. in IVC reaching up to inferior border of right atrium. Then USG guided biopsy done and Leiomyosarcoma of IVC was diagnosed by immunohistochemistry. Due to extensive involvement of intrahepatic segment and right atrium complete resection of mass was not possible, so radiotherapy followed by chemotherapy was started. Patient started deteriorating due to intolerability with poor response to radiotherapy and chemotherapy so he was put on supportive treatment.


Keywords


Inferior vena cava, Leiomyosarcoma, Right atrium, Vascular tumor

Full Text:

PDF

References


Mingoli A, Cavallaro A, Sapienza P. International registry of inferior vena cava leiomyosarcoma: analysis of a world series on 218 patients. Anticancer Res. 1996;16:3201-5.

Perl L. Ein Fall von Sarkom der Vena cava inferior. Virchows Arch. 871;53:378-83.

Hemant D, Krantikumar R, Amita J, Chawla J, Ranjeet N. Primary leiomyosarcoma of inferior vena cava, a rare entity: Imaging features. Australas Radiol. 2001;45(4):448-51.

Mingoli A, Cavallaro A, Sapienza P, Di Marzo L, Feldhaus RJ, Cavallari N. International registry of inferior vena cava leiomyosarcoma: analysis of a world series on 218 patients. Anticancer Res. 1996;16(5b):3201-5.

Yadav R, Kataria K, Mathur SR, Seenu V. Leiomyosarcoma of Inferior vena cava: A case series of four cases. Indian J Pathol Microbiol. 2012;55(1):83-5.

Ahulwalia A, Saggar K, Sandhu P, Gupta K. Primary leiomyosarcoma of inferior vena cava: An unusual entity. Vascular. 2002;12(4):15-6.

Weiss SW, Goldblum JR. Enzinger and Weiss’s soft tumor: 5th ed. Mosby Elsevier: Philadelphia, USA; 2008:545-562.

Monig SP, Gawenda M, Erasmi H, Zieren J, Pichlmaier H. Diagnosis treatment and prognosis of leiomyosarcoma of inferior vena cava. Eur J Surg. 1995;161(4):231-5.

Shindo S, Matsumoto H, Ogata K. Surgical treatment of retroperitoneal leiomyosarcoma invading the inferior vena cava: report of three cases. Surg Today. 2002;32:929-33.

Smillie RP, Shetty M, Boyer AC, Madrazo B, Jafri SZ. Imaging evaluation of the inferior vena cava. RG. 2015;35(2):578-92.