Herpes zoster as a presentation of diabetes mellitus

Authors

  • Vivek Kumar Verma Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India
  • Vidya Sagar Ram Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India
  • Prem Shanker Singh Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India
  • Manoj Kumar Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India
  • Sankalp Awasthi Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India
  • Dheeraj Kela Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20171810

Keywords:

Diabetes mellitus, Herpes zoster, Impaired glucose tolerance, Immunocompromised state

Abstract

Background: Herpes zoster (HZ) occurs due to reactivation of latent Varicella zoster virus infection and affects in dermatomal pattern. HZ affects elderly and immunocompromised population. Some earlier studies shows that HZ is common in diabetes patients. Our aim was to find out incidence of diabetes mellitus in patients with HZ.

Methods: Study was done on newly diagnosed HZ patients attending out door of UPUMS Saifai. Inclusion criteria include newly diagnosed case of HZ without previous history of diabetes. Patients with known immunocompromised state like HIV infection, corticosteroid therapy, chemotherapy, neoplastic disease etc were excluded. Fasting, post-prandial blood sugar and HbA1C of all patients done.

Results: 22.54% patients with HZ had diabetes and 7.75% patients had impaired glucose tolerance at presentation. Undiagnosed diabetes is common in HZ patients.

Conclusions: Our study indicates that incidence of undiagnosed diabetes is high among HZ patients and hence routine screening for diabetes should be done in all HZ patients.

Author Biographies

Vivek Kumar Verma, Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India

Senior Resident 

Department of Medicine

UP University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India - 206130

Vidya Sagar Ram, Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India

Assistant Professor

Department of Medicine

Prem Shanker Singh, Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India

Prof & Head

Department of Medicine

Manoj Kumar, Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India

Associate Professor

Department of Medicine

Sankalp Awasthi, Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India

Assistant Professor

Department of Dermatology

Dheeraj Kela, Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India

Postgraduate Junior Resident

Department of Medicine

 

References

Cohen JI. Clinical practice: herpes zoster. N Engl J Med. 2013;369:255-63.

Whitley R. Varicella-Zoster virus. In: Mandell G, Bennett J, Dolin R. editors. Principles and practice of infectious disease. 6 nd ed. Philadelphia: Churchill - Livingstone ;2005:1781-5.

Yawn BP, Saddier P, Wollan PC, Sauver JL, Kurland MJ, Sy LS. A population-based study of the incidence and complication rates of herpes zoster before zoster vaccine introduction. InMayo Clinic Proceedings. 2007;82(11):41-9.

Murea M, Ma L, Freedman BI. Genetic and environmental factors associated with type 2 diabetes and diabetic vascular complications. Rev Diabet Stud. 10;9(1):6-22.

Diabetes Care. 2004 Jan;27 Suppl 1:S5-S10. Available from: https://doi.org/ 10.2337/ diacare.

Mandal BK. Herpes zoster in the immunocompromized populations. Indian J Dermatol. 2006;51:235-43.

Burns T, Breathnach S, Cox N, Christopher G. Rook's textbook of dermatology, 7th ed. Massachusetts: Blackwell. 2004:22-8.

Mazur MH, Dolin R. Herpes zoster at the NIH: A 20-year experience. Am J Med. 1978;65:738-44.

Buse J, Polansky K, Burant C. Disorders of carbohydrate and lipid metabolism. In: Kronenbrey H, Melmed S, Polansky K, Larsen R, editors. Kroneberg: Williams textbook of endocrinology, 11th ed. Philadelphia: Saunders. 2008:1357-9.

Neu I, Rodiek S. Significance of diabetes mellitus in the activation of the varicella zoster virus. MMW Munch Med Wochenschr. 1977;119:543-6.

Guidetti D, Gabbi E, Motti L, Ferrarini G. Neurological complications of herpes zoster. Ital J Neurol Sci. 1990;11:559-65.

Najadawi F, Faouri M. Frequency and types of skin disorders and associated diabetes mellitus elderly Jordanians. East Mediterr Health J. 2002;8:574-8.

McCulloch DK, Fraser DM, Duncan LP. Shingles in diabetes mellitus. Practitioner. 1982;226:531-2.

Brown GR. Herpes zoster: Correlation of age, sex, distribution, neuralgia and associated disorders. South Med J. 1976;69:576-8.

Cerny Z. Recurrent eruptions of herpes zoster. Bratisl Lek Listy. 1999;100:515-8.

Ragozzio MW, Melton LJ, Kurland LT. Herpes zoster and diabetes mellitus: An epidemiological investigation. J Chronic Dis. 1983;36:501-5.

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Published

2017-04-26

How to Cite

Verma, V. K., Ram, V. S., Singh, P. S., Kumar, M., Awasthi, S., & Kela, D. (2017). Herpes zoster as a presentation of diabetes mellitus. International Journal of Research in Medical Sciences, 5(5), 1878–1881. https://doi.org/10.18203/2320-6012.ijrms20171810

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Section

Original Research Articles