A study on the histopathological pattern of thyroid lesions in a tertiary care hospital

Authors

  • Elizabeth Joseph Department of Pathology,MOSC Medical College, Kolenchery, Kerala, India
  • Anju Varghese Department of Biochemistry,MOSC Medical College, Kolenchery, Kerala, India
  • Celine T. M. Department of Community Medicine, MOSC Medical College, Kolenchery, Kerala, India
  • Anna Matthai Department of Pathology,MOSC Medical College, Kolenchery, Kerala, India
  • Usha Poothiode Department of Pathology,MOSC Medical College, Kolenchery, Kerala, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20164189

Keywords:

Thyroidectomy specimens, Multi nodular goiter, Thyroiditis, Thyroid carcinoma, Papillary carcinoma

Abstract

Background: Thyroid diseases are one of the most common endocrine disorders affecting the general population. They range from non-neoplastic to neoplastic lesions. The prevalence and pattern of these disorders depend on various factors including sex, age, ethnic and geographical patterns. The aim of the present study was to determine the pattern of thyroid lesions in thyroidectomy specimens received in the pathology department of MOSC Medical College Hospital, Kolenchery, Kerala, India.

Methods: It was a 6 year retrospective study (January 2010 to December 2015) of all thyroidectomy specimens received in the Pathology department. All the biopsy reports were reviewed and different lesions were categorized according to age and gender distribution.

Results: There were a total of 801 specimens, of which 716 were females and 85 were males. Maximum number of thyroid lesions were seen in the age group 41-50 yrs. Multinodular goiter was the most common non-neoplastic thyroid lesion (71.5%) followed by thyroiditis. There were 151 carcinomas (18.8%). Maximum numbers of carcinomas were seen in age group 31-40 (28.8%).The frequency of carcinomas among the total thyroid lesions was almost same for both males and females (18.82% and 18.85%). Papillary carcinoma was the most frequent malignancy, out of which half were of the micro papillary subtype.

Conclusions: Multinodular goiter was found to be the most common thyroid lesion in this study. The percentage of malignant thyroid tumors was high compared to other studies done in Kerala. Papillary carcinoma was the most common malignant neoplasm. The micropapillary variant comprised 50% of the papillary carcinoma.

References

Kochupillai N. Clinical endocrinology in India. CurrSci. 2000;79:1061-7.

Bayliss R. Thyroid disease. The fact, Oxford University press. New York. Toronto. 1982.

Mackenzie EJ, Mortimer RH. Thyroid nodules and thyroid cancer. Med J Aust. 2004;180:242-7.

Welker MJ, Orlov D. Thyroid nodules. Am Fam Physician. 2003;67:559-66.

Elahi S, Manzoor-ul-Hassan A, Syed Z, Nazeer L, Nagra S, Hyder S. A study of goiter among female adolescents referred to centre for nuclear medicine, Lahore. Pak J Med Sci. 2005;21:56-62.

Hussain N, Anwar M, Nadia N, Ali Z. Pattern of surgically treated thyroid diseases in Karachi. Biomedica. 2005;21:18-20.

Darwish AH, Al Sindi KA, El Kafsi J, Bacantab M. Pattern of thyroid diseases-A Histopathological Study. Bahrain Medical Bulletin. 2006;28:1-6.

Sushel C, Khanzada TW, Zulfikar I, Samad A. Histopathological pattern of diagnoses in patients undergoing thyroid operations. Rawal Med J. 2009;34:14-6.

Bukhari U, Sadiq S. Histopathological audit of goiter: A study of 998 thyroid lesions. Pak J Med Sci 2008;24:442-6.

Galofre JC, Lomvardlias S, Davies TF. Evaluation and treatment of thyroid nodules: a clinical guide. Mt Sinai J Med. 2008;75:299-311.

Morganti S, Ceda GP, Saccani M, Milli B, Ugolotti D, Prampolini R, et al. Thyroid disease in the elderly: sex-related differences in clinical expression. J Endocrinol Invest. 2005;28(11 Suppl Proceedings ):101-4

Elhamel A, Sherif I, Wassef S. The Pattern of Thyroid Disease in Closed Community of 1.5 Million People. Saudi Med J. 1988;9:481-4.

Tsegaye B, Ergete W. Histopathological pattern of thyroid disease. East African Med J. 2003;80:525-8.

Ashwini K, Anitha B, Letha P. Pattern of thyroid disorder in thyroidectomy specimen. Inter J Med Scie Pub Health. 2014;3:1446-8.

Downloads

Published

2016-12-16

How to Cite

Joseph, E., Varghese, A., M., C. T., Matthai, A., & Poothiode, U. (2016). A study on the histopathological pattern of thyroid lesions in a tertiary care hospital. International Journal of Research in Medical Sciences, 4(12), 5252–5255. https://doi.org/10.18203/2320-6012.ijrms20164189

Issue

Section

Original Research Articles