Neurodevelopmental outcome of babies with hypoxic ischemic encephalopathy
DOI:
https://doi.org/10.18203/2320-6012.ijrms20173012Keywords:
Amiel Tison angles, CDC grading of motor milestones, Early intervention, Hypoxic ischemic encephalopathy, Neurodevelopmental outcome, Trivandrum development screening chartAbstract
Background: The aim of the study was to find out the neurodevelopmental outcome of babies with hypoxic ischemic encephalopathy at 6 months of age and to predict early markers of abnormal neurological outcome in those babies.
Methods: 50 babies admitted with hypoxic ischemic encephalopathy were enrolled in this prospective study and followed up at 3 and 6 months of age at Mahatma Gandhi Memorial Government Hospital, Trichy. The neurological outcome of the babies was assessed by CDC grading of motor milestones, Trivandrum development screening chart, Amiel Tison angles head circumference and weight measured. USG cranium was done for all the babies and MRI brain was done in babies with abnormal neuro sonogram and abnormal outcome. Vision and hearing were tested clinically.
Results: The incidence of abnormal neurological outcome was 14%. The early markers predicting abnormal neurological sequele are identified.
Conclusions: Early identification of abnormal neuro behaviour helps in starting early intervention to improve the long term outcome.
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References
Jehan I, Harris H, Salat S, Zeb A, Mobeen N, Pasha O, et al. Neonatal mortality, risk factors and causes: a prospective population-based cohort study in urban Pakistan. Bulletin of World Health Org. 2009; 87:81-160.
Ekwochi U, Ndu IK, Nwokoye IC, Ezenwosu OU, Amadi OF, Osuorah DIC. Pattern of morbidity and mortality of newborn admitted into the sick and special care unit of Enugo State University Teaching Hospital, Enugo State. Nigerian J Clin Practice. 2014;17(3):346-51.
Himmelmann K, Hagberg G, Beckung E, Hagberg B, Uvebrant P. The changing Panorama of cerebral palsy in Sweden XI. Prevalence and origin in birth period 1995-98. Acts Paediatr. 2005;94:287-94.
Cordes I, Roland EH, Lupton BA, Hill A. Early Prediction of the development of microcephaly after Hypoxic Ischemic Encephalopathy, In the full term newborn. Pediatrics. 1994;93:703-7.
Levene MI, Lilford RJ. Management and outcome of Birth asphyxia. Fetal and neonatal neurology and neurosurgery London: Churchill Livingstone; 1995: 427-442.
Mizrahi EM, Kellaway P. Characterization and classification of seizures. Neurol. 1987;37:1837-44.
Robertson CMT, Perlman M. Follow up of the term infant after hypoxic Ischemic encephalopathy. Pediatrics Child health. 2006;11(5):278-82.
Baburaj S, Abraham B, Vasant PV, Raj S, Mohandas MK. Growth and development of high risk graduates till one year from a rural neonatal intensive care unit in South India. Int J Biomed Res. 2013;4(12):695-700.
Padayachee N, Ballot DE. Outcome of neonates with perinatal asphyxia at a tertiary academic hospital in Johannesburg, South Africa. SAJCH. 2013;7:89-94.
Zafar M, Sheela L. A study on prevalence and antecedents of developmental delay among children less than 2 years attending well baby clinic. People’s J Sci Res. 2009;2(1):9-12.
Misra PK, Srivastava N, Malik GK, Kapoor RK, Srivastava KL, Rastogi S. Outcome in relation to Apgar score in term neonates. Indian Paediatr. 1994;31(10):1215-8.
Gonzalez de Dios J, Moya M. Perinatal asphyxia, hypoxic ischemic encephalopathy and neurological sequelae in full term newborns. Rev Neurol. 1996;24(132):969-76.
Kaye D. Antenatal and Intrapartum Risk Factors for birth asphyxia among emergency obstetric referrals in Mulego Hospital. East African Med J. 2003;80(3):140-3.
Abdulqawi K, Al-Zohairy YZ, Karam K. Early predictors of neuro developmental adverse outcome in term infants with post asphyxia hypoxic ischemic encephalopathy. Int J Collaborative Res Internal Med Public Health. 2011;3(11):822-37.
Carli G, Reiger I, Evans N. One year neuro developmental outcome after moderate newborn hypoxic ischemic encephalopathy. J Pediatr Child Health. 2004;40(4):217-20.
Elenjickal MG, Thomas K, Sushamabai S, Sheik K, Ahamed Z. Development of High Risk Newborns -A follow up study from birth to one year. Indian Paediatr. 2009;46:342-5.
Godbole K, Barve S, Chaudhari S. Early predictors of neuro developmental outcome of high risk infants. Indian Paediatr. 1997;34:491-5.
Chaudhari S, Deo B. Neuro developmental Assessment in the first year with emphasis on evolution of tone. Indian Paediatr. 2006;43:527-34.
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