DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20173551

Role of fine needle aspiration cytology in diagnosis of breast lumps

Prashant S. Mane, Aparna M. Kulkarni, Ravindra V. Ramteke

Abstract


Background: Breast cancer is the most common cancer in women worldwide. Fine needle aspiration cytology is a cost effective, easy procedure in the diagnosis of breast lump.

Methods: This was a one year retrospective study between January 2016 and December 2016. Needle aspiration was done in 100 patients presenting with breast lump. Histopathology correlation was done in 33 cases.

Results: Fibroadenoma were most common lesions. Malignancy was reported in 13 cases. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy were found to be 85%, 100%, 100%, 96.3% and 97% respectively.

Conclusions: Fine needle aspiration cytology is a simple, easy, OPD based, cost effective procedure with high sensitivity, specificity and accuracy in diagnosis of breast lumps.


Keywords


Breast, Cancer, Cytology, Fibroadenoma, Lump

Full Text:

PDF

References


Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C, et al. GLOBOCAN 2012 v1.1, Cancer Incidence and Mortality Worldwide: IARC Cancer Base No. 11 (Internet). Lyon, France: International Agency for Research on Cancer; 2014. Available at http://globocan.iarc.fr, accessed on 16/01/2015.

Gupta S. Breast cancer: Indian experience, data, and evidence. South Asian J Cancer. 2016;5:85-6.

Ahmed I, Nazir R, Chaudhary MY, Kundi S. Triple assessment of breast lump. J Coll Physicians Surg Pak. 2007;17:535-8.

Iqbal MH, Iqbal K, Nadeem A. Diagnostic accuracy of fine needle aspiration cytology (FNAC) in patients with breast lump. PJMHS Dec. 2015;9(4):1210-2.

Koss LG, Melamed MR. Koss' diagnostic cytology and its histopathologic bases, 5th Edition. New York (USA): Lippincott Williams and Wilkins; 2005.

Martin HE, Ellis EB. Biopsy by needle puncture and aspiration. Ann Surg. 1930;92:169-81.

Tiwari M. Role of fine needle aspiration cytology in diagnosis of breast lumps. Kathmandu University Med J. 2007;5(18):215-7.

Singh S, Chandra P, Jitendra. Diagnostic accuracy of fine needle aspiration cytology of breast lump in rural population of Western U.P. Sch J App Med Sci. 2015;3(1):467-9.

Jarwani PB, Patel DC, Patel SM, Dayal A. Fine Needle aspiration cytology in a palpable breast lump. GCSMC J Med Sci Dec. 2013;2(2):12-6.

Likhar KS, Fatima A, Hazari RA, Gupta SG, Shukla U. Diagnostic role of FNAC in breast lesions. IJRRMS. 2013;3(1):12-4.

Modi P, Oza H, Bhalodia J. FNAC as preoperative diagnostic tool for neoplastic and non-neoplastic breast lesions: a teaching hospital experience. National J Med Res. 2014;4(4):274-8.

Saraf S, Khare M, Kalgutkar A. Fine needle aspiration cytology of breast lumps- a correlation with histopathology diagnosis. In J Pathol Oncol. 2016;3(1);103-6.

Singh P, Chaudhry M, Nauhria S, Rao D. Cytomorphological patterns of breast lesions diagnosed on fine-needle aspiration cytology in a tertiary care hospital. Int J Med Sci Public Health. 2015;4(5):674-9.

Mitra S, Dey P. Grey zone lesions of breast: potential areas of error in cytology. J Cytol. 2015;32(3):145-52.

Shabb NS, Boulos FI, Abdulkarim FW. Indeterminate and erroneous fine-needle aspirates of breast with focus on the ‘true gray zone’: a review. Acta Cytologica. 2013;57:316-31.

Panjvani SI, Parikh BJ, Parikh SB, Chaudhari BR, Patel KK, Gupta GS, et al. Utility of fine needle aspiration cytology in the evaluation of breast lesions. J Clin Diagnostic Res. 2013;7(12):2777-9.