DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20173540

Cross-sectional descriptive observational study of RT PCR proven category C H1N1 patients at tertiary care centre from January 2015- December 2015

Anita A. Paritekar, Mahendra V. Bansode, Anushka K. Waikar, Rohidas T. Borse

Abstract


Background: The onset of winter of 2014-2015 saw an alarming spurt in influenza A (H1N1) pdm 09 leading to a significant mortality. H1N1 primarily affects the very young, elderly, pregnancy and those patients with comorbidities. But the epidemiologic hallmark of pandemic influenza is its "pandemic signature " meaning most early mortalities are among young healthy adults.

Methods: To study clinical profile, premorbid conditions and radiological features of Category C H1N1 proven by RTPCR retrospectively from hospital records from Jan 2015 to Dec 2015 at Tertiary Care Centre.

Results: Total 108 cases RT PCR proven category C H1N1 studied from hospital records. 43 were males and 65 females. The mean age group was 50 years for males and 40 for females. Common symptoms were fever, cough, dyspnoea with pre-morbid illness like hypertension, diabetes mellitus, pregnancy, cancer and immune compromised with pulmonary tuberculosis. Radiologically there was lower zone involvement common in live patients and reticulonodular was common in death cases.

Conclusions: In current study young to middle age group was commonly affected. Pre-morbid conditions, more than two risk factors and late referral were the most common findings in death cases.


Keywords


H1N1 virus, Swine flu

Full Text:

PDF

References


Mishra B. Resurgence of influenza a (H1N1) 09: Smouldering pandemic in India? J Global Infectious Dis. 2015;7(2):56.

Sharma R, Agarwal S, Mehta S, Nawal CL, Bhandari S, Rathore M, et al. Profiling the mortality due to influenza A (H1N1) pdm 09 at a tertiary care hospital in Jaipur during the current season-January and February 2015. J Assoc Physicians India. 2015;63.

Itolikar S, Nadkar MY. H1N1 revisited after six years: then and now. J Assoc Physicians India. 2015;63(4):41-3.

Borse RT, Kadam DB, Sangle SA, Basavraj A, Prasad HB, Umarji PB, et al. Clinic radiologic correlation in adult patients diagnosed with novel influenza A (H1N1). J Assoc Physicians India. 2013;61:600-7.

Puvanalingam A, Rajendiran C, Sivasubramanian K, Ragunanthanan S, Suresh S, Gopalakrishnan S. Case series study of the clinical profile of H1N1 swine flu influenza. J Assoc Physicians India. 2011;59(14.16).

Borse RT, Kadam DB, Sangle SA, Basavraj A, Prasad HB, Umarji PB, et al. Comparison of demographic, clinical, radiological characteristics and comorbidities in mechanically ventilated and nonventilated, adult patients admitted in ICU with confirmed diagnosis of influenza A (H1N1). J Assoc Physicians India. 2013;61(12):887-93.

Jain S, Kamimoto L, Bramley AM, Schmitz AM, Benoit SR, Louie J, et al, Hospitalised patients with H1N1 influenza in the United States, April June 2009. N Eng J Med. 2009:361:1935-44.

Aviram G, Bar-Shai A, Sosna J, Rogowski O, Rosen G, Weinstein I, et al. H1N1 Influenza: initial chest radiographic findings in helping predict patient outcome 1. Radiol. 2010;255(1):252-9.

Panchal VD, Desai P, Vadel MK. Role of chest x-ray in assessing the severity in H1N1 influenza cases. National J Med Res. 2015;5(4):305-8.

Perez-Padilla R, De La Rosa-zamboni D, Ponce de Leon S, Hernandez M, Quinones-Falconi F, Bautista E, et al. Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in Mexico. New England J Med. 2009;361(7):680-9.