Effect of cissus quadrangularis linn and zingiber officinale rosc in osteoarthritis patients


  • J. Viswanath Department of Dravyaguna, Sri Adi Siva Sadguru Allisaheb Sivaaryula Ayurvedic Medical College Guntakal, Andhra Pradesh, India
  • Chakrapani Cheekavolu Department of Pharmacology, Kerala Medical College and hospital, Mangode, Palakkad, Kerala, India
  • S. Sankaraiah Department of Dravyaguna, S. V. Ayurvedic Medical College, Tirupathi, Andhra Pradesh, India
  • Renu Dixit Department of Dravyaguna, S. V. Ayurvedic Medical College, Tirupathi, Andhra Pradesh, India




Cissus quadrangularis linn, Osteoarthritis, Zingiber officinale rosc


Background: To evaluate the efficacy of Cissus quadrangularis Linn. or Zingiber officinalis Rosc. or in combination treatment of osteoarthritis which reduces joint pain, joint swelling and tenderness without risk of side effects.

Methods: Total 60 patients were selected and divided into 3 groups (each group consist of 20 patients); data were collected before and after treatment of following groups: Group A-Cissus quadrangularis linn-5gm; Group B- Zingiber officinale rosc-5gm; Group C-Treatment of Cissus quadrangularis linn combined with Zingiber officinale rosc-5 gm/dose twice a day with luke warm water.

Results: 60 % cases of joint pain were relieved at the end of the treatment in group B & C, in group A 50%, reduction in joint pain extremely significant in all groups A, B, C (p<0.0001). ‘C’ 80%, ‘A’ 15% and ‘B’5% reduction in symptom of Joint swelling and which is very significant in group A, and group B (p<0.001) and extremely significant in group C (p<0.0001). Symptom of tenderness ‘C’ 90%, ‘A’ 85%, and ‘B’ 10% cases were relived from the complaint. The difference in tenderness is statistically extremely significant when compared between groups (p<0.0001).

Conclusions: Present study reveals that, significant reduction of joint pain, joint swelling and tenderness after treatment of Cissus quadrangularis Linn. or Zingiber officinalis Rosc. and extremely significant reduction of joint swelling and tenderness in combination therapy.


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How to Cite

Viswanath, J., Cheekavolu, C., Sankaraiah, S., & Dixit, R. (2017). Effect of cissus quadrangularis linn and zingiber officinale rosc in osteoarthritis patients. International Journal of Research in Medical Sciences, 5(8), 3540–3544. https://doi.org/10.18203/2320-6012.ijrms20173558



Original Research Articles