Study of the causes and factors which affect compliance of the patient in directly observed short course chemotherapy in pulmonary tuberculosis in Central India

Authors

  • Vivek Saxena Department of Medicine, Chirayu Medical College and Hospital, Bhopal, Madhya Pradesh, India
  • Shreshtha Saxena Department of Obstetrics and Gynecology, Sai Seva Hospital, Sehore, Madhya Pradesh, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20172974

Keywords:

DOTS, Pulmonary tuberculosis, Revised national tuberculosis programme

Abstract

Background: TB is one of the most ancient diseases. World Health Organization (WHO) estimated 9.2 million new cases in 2014 out of which 2.2 million were from India. National tuberculosis programme was started since 1962 and short course chemotherapy was included in 1983. With this background in 1992 WHO and Swedish International Development Agency (SIDA) reviewed the programme. As a result, revised national tuberculosis programme (RNTCP) was started. RNTCP recommended directly observed short course chemotherapy in pulmonary tuberculosis (DOTS) and was implemented in 1993. Objective of present study was to find out the causes and factors affecting compliance of the patients in directly observed short course chemotherapy in pulmonary tuberculosis.

Methods: We studied 100 patients of pulmonary tuberculosis, who were sputum smear positive for tubercle bacilli. Patients were treated with DOTS (Directly Observed Short Course Chemotherapy) recommended by RNTCP and we observed the causes and factors responsible for interruption of the treatment in noncompliant patients.

Results: Overall compliance was 78% and 22% patients were noncompliant. Most common cause of noncompliance was side effects of drugs (12%), noncompliance was maximum (45.45%) between age group of 15-25 years. Illiterate and low socioeconomic status patients were more noncompliant 46.45% and 63.63% respectively.

Conclusions: Eventually, after seeing all merits and demerits of DOTS, we have concluded that intensive health education may have favourable impact to improve further outcome of DOTS and compliance of the patients.

Author Biographies

Vivek Saxena, Department of Medicine, Chirayu Medical College and Hospital, Bhopal, Madhya Pradesh, India

DEPARTMENT OF MEDICINE, ASSOCIATE PROFESSOR

Shreshtha Saxena, Department of Obstetrics and Gynecology, Sai Seva Hospital, Sehore, Madhya Pradesh, India

department of medicine, associate professor

References

Global Tuberculosis Control 2015, WHO, Geneva, 2015. Available at http://www.tbfacts.org/tb-statistics-india/#sthash.HIitL99m.dpuf.

Sachdeva KS, Kumar A, Dewan P, Kumar A, Satyanarayana S. New Vision for Revised National Tuberculosis Control Programme (RNTCP): Universal access Reaching the un-reached. Indian J Med Res. 2012;135(5):690.

Smirnoff M, Goldberg R, Indyk L, Adler JJ. Directly observed therapy in an inner-city hospital. Int J Tuberc Lung Dis. 1998;2(2):134-9.

Alcaide Megias J, Pascual Torramade J, Altet Gómez MN, Maldonado Diaz de Losada J, Lopez Espinosa F, Salleras Sanmarti L. Results and epidemiological impact of directly observed treatment of tuberculosis. Arch Bronconeumol. 1999;35(6):267-74.

Polo Friz H, Kremer L, Acosta H, Abdala O, Canova S, Rojo S, et al. Treatment with tuberculostatic drugs: compliance at a general hospital. Rev Fac Cien Med Univ Nac Cordoba. 1997;55(1-2):21-5.

Burman WJ, Cohn DL, Rietmeijer CA, Judson FN, Reves RR, Sbarbaro JA. Noncompliance with directly observed therapy for tuberculosis: epidemiology and effect on the outcome of treatment. Chest. 1997;111(5):1168-73.

Prasad R, Rizavi DM, Kant S, Jain A. A comparison of unsupervised treatment along with intensive health education and directly observedtreatment in pulmonary tuberculosis. Indian J Tuberc. 2001;48:21

Balasubramanian VN, Oommen K, Samuel R. DOT or not? Direct observation of anti-tuberculosis treatment and patient outcomes, Kerala State, India. Int J Tuberc Lung Dis. 2000;4(5):409-13.

Downloads

Published

2017-06-24

How to Cite

Saxena, V., & Saxena, S. (2017). Study of the causes and factors which affect compliance of the patient in directly observed short course chemotherapy in pulmonary tuberculosis in Central India. International Journal of Research in Medical Sciences, 5(7), 2989–2992. https://doi.org/10.18203/2320-6012.ijrms20172974

Issue

Section

Original Research Articles