DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20164536

Evaluation of the pulse wave velocity in African rheumatoid arthritis subjects

Maïmouna Touré, Valentin Ouédraogo, Demba Dièdhiou, Moustapha Niasse, Souleymane Thiam, Coumba Diouf, Abdou Khadir Sow, Mor Diaw, Arnaud Jean Florent Tiendrébéogo, Aïssatou Seck, Salimata Diagne Houndjo, Abdoulaye Ba, Magid Hallab, Georges Lefthériotis, Abdoulaye Samb

Abstract


Background: Rheumatoid arthritis is a systemic disease with often fatal vascular events. In addition to traditional cardiovascular risk factors, disease-specific elements contribute to this cardiovascular mortality. The aim of this study was to assess arterial stiffness in rheumatoid arthritis and to determine the factors involved.

Methods: We have recruited the black African patients followed in rheumatology and had rheumatoid arthritis diagnosis. Only patients between 18 and 60 years and meeting the American College of Rheumatology criteria were included. All controls were healthy. We evaluated the propagation velocity of the pulse wave finger-toe (PWVft) measured by the pOpmètre®.

Results: Present study shows that the PWVft was significantly elevated in over half of patients (55.10%). Besides, the mean patients PWVft was significantly higher than that of the control (respectively 9.40±0.51 and 7.22±0.33 p=0.001). In the patients, no factor was significantly involved in the arterial stiffness, but cons in the control group, the PWVft was significantly correlated with age (p=0.023 and r=0.55).

Conclusions: Rheumatoid arthritis patients had higher PWVft compared to controls. Due to the importance of its cardiovascular morbidity and mortality, arthritis requires a regular monitoring element as arterial stiffness, which is currently a major vascular parameter monitoring.

Keywords


African black, Arterial stiffness, Rheumatoid arthritis

Full Text:

PDF

References


Daïen CI, Fesler P. Rheumatoid arthritis: a cardiovascular disease? Ann Cardio Angio. 2012;61:111-7.

Watson DJ, Rhodes T, Guess HA. All-cause mortality and vascular events among patients with rheumatoid arthritis, osteoarthritis, or no arthritis in the UK General Practice Research Database. J Rheumatol 2003;30:1196-202.

Soubrier M, Barber Chamoux N, Tatar Z, Couderc M, Dubost JJ, Mathieu S. Cardiovascular risk in rheumatoidarthritis. Joint Bone Spine. 2014;81:298-302.

Kerola AM, Kauppi MJ, Kerola T, Nieminen TV. How early in the course ofrheumatoid arthritis does the excess cardiovascular risk appear? Ann RheumDis 2012;71:1606-15.

Semerano L, Clavel G, Boissier MC. Vessels in rheumatoid arthritis: a therapeutic target. Rheumatism Review. 2010;77:S3-S9.

Solomon DH, Curhan GC, Rimm EB, Cannuscio CC, Karlson EW. Cardiovascular risks in women with and without rheumatoid arthritis. Arthritis Rheum. 2004;50:3344-9.

Arnett FC, Edworthy SM, Bloch DA, Mc Shane DJ, Fries JF, Cooper NS, et al. The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988;31:315-24.

Hallab M, Collette M, Terrier-Barbeau C, Legrand M, Ducluzeau PH, Berrut G, et al. Arterial stiffness measured by pOpmeter® in patients at cardiovascular risk, link to carotid atheroma plaques. Ann Cardio Angio. 2013;62:189-92.

Van Doormun S, McColl G, Jenkins A, Green DJ, Wicks IP. Screening for atherosclerosis in patients with rheumatoid arthritis. Comparison of two in vivo tests of vascular function. Arthritis Rheum. 2003;28:72-80.

Klocke R, Cockcroft JR, Taylor GJ, Hall IR, Blake DR. Arterial stiffness and central blood pressure as determined by pulse wave analysis, in rheumatoid arthritis. Ann Rheum Dis. 2003;62:414-8.

Provan SA, Angel K, Semb AG. Early prediction of increased arterial stiffness in patients with chronic inflammation: a 15-year follows up study of 108 patients with rheumatoid arthritis, J. Rheumatol. 2011;38:606-12.

Maradit-Kremers H, Nicola PJ, Crowson CS, Ballman KV, Gabriel SE. Cardiovascular death in rheumatoid arthritis. A population based study. Arthritis Rheum. 2005;52:722-32.

Wolfe F, Freundlich B, Straus WL. Increase in cardiovascular and cerebrovascular disease prevalence in rheumatoid arthritis. J Rheumatol. 2003;30:36-40.

Pham T, Gossec L, Constantin A. Cardiovascular risk and rheumatoid arthritis: clinical practice guidelines based on published evidence and expert opinion. Joint Bone Spine. 2006;73:379-87.

Semerano L, Clavel G, Boissier MC. Vessels in rheumatoid arthritis: a therapeutic target. Rheumatism Review. 2010;77:S3-9.

Del Rincon ID, Williams K, Stern MP, Freeman GL, Escalante A. High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors. Arthritis Rheum 2001;44:2737-45.

Soubrier M, Dougados M. Atheroma and rheumatoid arthritis. Inter Med J. 2006;27:125-36.

Schmidt-Trucksass A, Gratwohl D, Schmid A, Boragk R, Upmeier C, Keul J. Structural, functional and haemodynamic changes of the common carotid artery with age in male subjects. Arterioscler Thromb Vasc Biol. 1999;19:1091-7.