Evaluation of the pulse wave velocity in African rheumatoid arthritis subjects

Maïmouna Touré; Valentin Ouédraogo; Demba Dièdhiou; Moustapha Niasse; Souleymane Thiam; Coumba Diouf; Abdou Khadir Sow; Mor Diaw; Arnaud Jean Florent Tiendrébéogo; Aïssatou Seck; Salimata Diagne Houndjo; Abdoulaye Ba; Magid Hallab; Georges Lefthériotis; Abdoulaye Samb

doi:10.18203/2320-6012.ijrms20164536

Authors

Maïmouna Touré Laboratory of Human Physiology and Functional Explorations / FMPO / UCAD / UMI 3189 UCAD / CNRST / Senegal
Valentin Ouédraogo Laboratory of Human Physiology and Functional Explorations / FMPO / UCAD / UMI 3189 UCAD / CNRST / Senegal
Demba Dièdhiou Medical Clinic Service II / FMPO / UCAD / Dakar / Senegal
Moustapha Niasse Department of Rheumatology, CHU Aristide LeDantec / UCAD / Dakar / Senegal
Souleymane Thiam Laboratory of Biochemistry / FMPO / UCAD / Dakar / Senegal
Coumba Diouf Department of Rheumatology, CHU Aristide LeDantec / UCAD / Dakar / Senegal
Abdou Khadir Sow Laboratory of Human Physiology and Functional Explorations / FMPO / UCAD / UMI 3189 UCAD / CNRST / Senegal
Mor Diaw Laboratory of Human Physiology and Functional Explorations / FMPO / UCAD / UMI 3189 UCAD / CNRST / Senegal
Arnaud Jean Florent Tiendrébéogo Laboratory of Human Physiology and Functional Explorations / FMPO / UCAD / UMI 3189 UCAD / CNRST / Senegal
Aïssatou Seck Laboratory of Human Physiology and Functional Explorations / FMPO / UCAD / UMI 3189 UCAD / CNRST / Senegal
Salimata Diagne Houndjo Laboratory of Human Physiology and Functional Explorations / FMPO / UCAD / UMI 3189 UCAD / CNRST / Senegal
Abdoulaye Ba Laboratory of Human Physiology and Functional Explorations / FMPO / UCAD / UMI 3189 UCAD / CNRST / Senegal
Magid Hallab University Hospital of Nantes, Place Ricordeau, 44000 Nantes - France
Georges Lefthériotis Laboratory of Integrated Neuro-vascular and Mitochondrial Biology UMR CNRS 6214 - Inserm 1083, Faculty of Medicine Angers, 49045 Angers - France
Abdoulaye Samb Laboratory of Human Physiology and Functional Explorations / FMPO / UCAD / UMI 3189 UCAD / CNRST / Senegal

DOI:

https://doi.org/10.18203/2320-6012.ijrms20164536

Keywords:

African black, Arterial stiffness, Rheumatoid arthritis

Abstract

Background: Rheumatoid arthritis is a systemic disease with often fatal vascular events. In addition to traditional cardiovascular risk factors, disease-specific elements contribute to this cardiovascular mortality. The aim of this study was to assess arterial stiffness in rheumatoid arthritis and to determine the factors involved.

Methods: We have recruited the black African patients followed in rheumatology and had rheumatoid arthritis diagnosis. Only patients between 18 and 60 years and meeting the American College of Rheumatology criteria were included. All controls were healthy. We evaluated the propagation velocity of the pulse wave finger-toe (PWVft) measured by the pOpmètre®.

Results: Present study shows that the PWVft was significantly elevated in over half of patients (55.10%). Besides, the mean patients PWVft was significantly higher than that of the control (respectively 9.40±0.51 and 7.22±0.33 p=0.001). In the patients, no factor was significantly involved in the arterial stiffness, but cons in the control group, the PWVft was significantly correlated with age (p=0.023 and r=0.55).

Conclusions: Rheumatoid arthritis patients had higher PWVft compared to controls. Due to the importance of its cardiovascular morbidity and mortality, arthritis requires a regular monitoring element as arterial stiffness, which is currently a major vascular parameter monitoring.

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