DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20173984

Prevalence of sensory peripheral neuropathy in diabetic patients at diabetes care centre: a cross sectional study

Pradeep Battula, S. Afreen, E. Meena, S. Siva Ram Reddy, G. Sujatha

Abstract


Background: Diabetic neuropathy is a nerve damaging disorder associated with diabetes; result from micro vascular injury involving small blood vessels that supply to the nerve (vas nervorum) in addition to macro vascular condition that can culminate in diabetic neuropathy. By the year 2025 hundreds of people were estimated to become diabetic. The rates of prevalence of neuropathy increasing worldwide which is directly related to the nonmodifiable risks like age, duration of diabetes, obesity, alcoholism, gender.

Methods: A cross sectional interventional study was conducted on diabetic patients. Questionnaire, instruments and demographic details were used to collect data from patients. The diabetic neuropathy is conformed in patients by using biothesiometric analysis, tuning fork, monofilament, NSS and NDS.

Results: Total 331 subjects included in the study, 200 cases diagnosed with DPN according to biothesiometry and prevalence percentage was found to be 60.4% and incidence was found to be 8.76% respectively. A significant greater proportion of males reported neuropathy more than females. The association between the obesity and the DPN was (r2=0.7922) low positive correlation. High positive correlation was confirmed with NSS, NDS respectively.

Conclusions: It was concluded that there is a higher prevalence (60.4%) and incidence (8.76%) of neuropathy among the diabetic subjects and it may go on increasing as the age progress.


Keywords


Biothesiometry, Diabetic peripheral neuropathy, Obesity, Prevalence

Full Text:

PDF

References


Boucek P. Advanced diabetic neuropathy: a point of no return. J Society Biomed Diab Res. 2006;3(3):143.

Feldman EL, Brown MB, Stevens MJ, Canal N, Thomas PK, Greene DA. A practical two step quantitative clinical and electrophysiological assessment for the diagnosis and staging of diabetic neuropathy. Diab Care. 1994;17(11):1281.

Zeigler D, Meisiner C, Rathmann W, Meisinger A, Dickhaus T. Prevalence of polyneuropathy in prediabetes and diabetes is associated with abdominal obesity and macroanigopathy. Diab Care. 2008;31(3):464.

Gill HK, Yadav SB, Ramesh V, Bhatia E. A prospective study of prevalence and association of peripheral neuropathy in Indian patients with newly diagnose type 2 diabetes mellitus. J Postgrad Med. 2014;60(3):2-3.

Popescu S, Timar B, Baderca F, Simu M, Diconu L, Velea I, et al. Age as an independent factor for the development of neuropathy in diabetic patients. Dovepress. 2016;11:313.

Ziegler D. Painful diabetic neuropathy. Diab Care. 2009;32(2):5414.

Ugoya S, Owolabi MO, Puepet FH, Echejoh GO, Ogunniyi A. Association between body mass index and diabetic peripheral neuropathy. Hungarian Med J. 2008;2(1):63.

Branwald F, Kasper, Longo H, Jameson, Loscalzo. Harrisons principles of internal medicine. 17th ed; 2008:2656.

9. Dipiro.JT, Talbert.RL, Yee.GC, Matzke.GR, Wells.BG, Posey.LM. Pharmacotherapy a pathophysiologic approach, 7th ed. 2008: 1234-1235.

Kamenov Z, Parapunov R, Georgieva R. Incidence of diabetic neuropathy. Clinic Endocrino. 2009;2(3):39-48.

Perkins BA, Olaleye D, Zinman B, Bril V. Simple screening tests for peripheral neuropathy in the diabetic clinic. Diab Care. 2001;24:250-6.

Haslbeck M, Luff D, Neuntorfer D, Ziegler D, Stracke H. Diagnosis, treatment and follow-up of diabetic neuropathy. 2004;2:9.

Digital biothesiometer: vibroscreen, user manual. Diabetic foot care India Pvt. Ltd.

Behse F, Buchthal F, Carlsen F. Nerve biopsy and conduction studies in diabetic neuropathy. J Neurol Neurosurg Psychiartry. 1997;40:1072-82.

Abbott CA, Kulkarni J, Malik RA, Boulton AJM, Ross ERE. Prevalence and characteristics of painful diabetic neuropathy in a large community- based diabetic population in the UK. Diab Care. 2011;34:2220-4.

Ashok S, Ramu M, Deepa R, Mohan V. Prevalence of neuropathy in type 2 diabetic patients attending a diabetic centre in south India. Madras Diabetes Research Foundation. 2001;50:546-50.

Kiani J, Moghimbigi A, Azizkhani H, Kosarifard S. The prevalence and associated risk factors of diabetic neuropathy in Hamedan, Iran. Arch Iranian Med. 2013;b16:1-2.

Sobhani S, Asayesh H, Sharifi F, Djalalinia S, Baradaran HR, Arzaghi SM, et al. Prevalence of diabetic peripheral neuropathy in Iran: a systematic review and meta-analysis. J Diab Metabol Disorders. 2014:13-97.

Mythili A, Kumar KD, Subramanyam KAV, Venkatesvarulu K, Butchi RG. A comparative study of examination scores and quantitative sensory testing in diagnosis of diabetic polyneuropathy. Int J Diab Developing Countries. 2010:1-10.

Hozumi J, Sumitani M, Matsubayashi Y, Abe H, Oshima Y, Chikuda H. Relationship between neuropathic pain and obesity, pain research and management. Pain Research Management 2016:6-10.