Clinical profile of babies with meconium stained amniotic fluid

Defairlin Ranee; Deepa S. Phirke

doi:10.18203/2320-6012.ijrms20174116

Authors

Defairlin Ranee Department of Pediatrics, Government Medical College, Miraj, Maharashtra, India
Deepa S. Phirke Department of Pediatrics, Government Medical College, Miraj, Maharashtra, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20174116

Keywords:

APGAR score, Meconium stained amniotic fluid (MSAF), Meconium aspiration syndrome (MAS), Thick MSAF

Abstract

Background: Meconium staining of amniotic fluid (MSAF) is a relatively common problem occuring in 10-25% of all deliveries. Meconium aspiration syndrome is more common in term babies than in preterm babies with rising frequency along with increase in gestational age of the fetus. Meconium stained amniotic fluid generally indicates sign of fetal distress. The objective of this study was to study clinical profile of meconium aspiration syndrome and the probable risk factors for meconium aspiration syndrome.

Methods: It is a prospective observational sectional study conducted in NICU of department of paediatrics of tertiary care centre from 1st January 2015 to 30th June 2016.

Results: In this study both sexes were equally affected, majority of the neonates were above 2.5kg and only very few (2 neonates) were less than 1.5kg. majority of the neonates were full term, it was found that there is a significant association between thick MSAF and the development of MAS, it was found that there is a significant association between low APGAR score at 1 minutes and the development of MAS, there is a strong association between thick MSAF and mortality in MSAF babies. Anemia 38 (25%) was the most frequent perinatal risk factor followed by fetal distress 27 (18) and PIH 21 (14%).

Conclusions: Newborns with thick MSAF were more likely to develop MAS and thick MSAF and low APGAR at 1 min were associated with high risk of development of MAS. Passage of thick meconium was significantly associated with severe birth asphyxia and carried a bad prognosis with increased risk of development of meconium aspiration syndrome and hypoxic ischaemic encephalopathy.

Metrics

Metrics Loading ...

Author Biographies

Defairlin Ranee, Department of Pediatrics, Government Medical College, Miraj, Maharashtra, India

Pediatrics Department, Rank -Resident

Deepa S. Phirke, Department of Pediatrics, Government Medical College, Miraj, Maharashtra, India

Paediatrics department, Associate Professor

References

Wiswell TE, Bent RC. Meconium staining and the meconium aspiration syndrome. Unresolved issues. Pediatric Clin North Am. 1993;40(5):955-81.

Ballard, Robert A. Respiratory failure in term infant; Meconium Aspiration Pneumonia; Avery’s disease of New born; 8th edition; 2005;48:712-4.

Woods JR, Glantz JC. Significance of amniotic fluid meconium. Maternal fetal medicine principles and practices. 3rd ed. Philadelphia: WB Saunders Company. 1994:413.

Davis RO, Philips JB, Harris BA, Wilson ER, Huddleston JF. Fatal meconium aspiration syndrome occurring despite airway management considered appropriate. Am J Obstet Gynecol. 1985;151(6):731-6.

Usta IM, Mercer BM, Sibai BM. Risk factors for meconium aspiration syndrome. Obstetr Gynecol. 1995;86(2):230-4.

Trimmer KJ, Gilstrap LC. “Meconiumcrit” and birth asphyxia. Am J Obstet Gynecol. 1991;165(4):1010-3.

Ahanya SN, Lakshmanan J, Morgan BL, Ross MG. Meconium passage in utero: mechanisms, consequences, and management. Obstet Gynecol Surv. 2005;60(1):45-56.

Narang A, Nair PM, Bhakoo ON, Vashisht K. Management of meconium stained amniotic fluid: a team approach. Indian Pediatr. 1993;30:9.

AV R, KL S, GM. A study on meconium aspiration syndrome cases attending to Government general hospital, Anantapuramu, Andhra Pradesh. Int J Res Health Sci. 2015;3(1):169-73.

Chandran JR, Uma DN, Rajeshwary U. Risk factors for meconium aspiration and MAS (meconium aspiration syndrome) in neonates born through meconium stained amniotic fluid (MSAF) in a tertiary care centre in Malabar (Kerala). J Evolut Med Dent Sci. 2013;2(49):9489-95.