Spindle cell sarcoma of sphenoid bone

Moorthy N. L. Nimmagadda, Vithaleswar M. Rao, Padmaja S., Harshini Reddy


Primary bone tumors involving skull are extremely rare and they constitute 0.8% of all bone tumors. The common tumors that are seen in skull base include fibrous dysplasia, giant cell tumor, chordoma, ossifying fibroma, angiosarcoma. We report a rare case of spindle cell sarcoma arising from right sphenoid bone in a 70-year-old male which presented as unilateral defective vision with mild proptosis.


MR imaging, Sphenoid bone, Spindle cell sarcoma

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Haetinger R. Tumors affecting primary the sphenoid region-a review of the main lesions. European Congress of Radiol; 2011.

Ishikawa T, Yashima S, Hasan H, Shimosato T, Imada S. Osteoma of the lateral pterygoid plate of sphenoid bone Int J Oral Maxillofac Surg. 1986;15(6):786-9.

Ciappetta P, Salvati M, Raco A, Artico M, Gagliardi FM Benign osteoblastoma of the sphenoid bone.Neurochirurgia (Stuttg). 1991;34(3):97-100.

Bozbuga M, Turan Suslu H. Aneurysmal bone cyst of the sphenoid bone extending into the ethmoid sinus, nasal cavity and orbita in a child. Turk Neurosurg. 2009;19(2):172-6.

Cansiz H, Inci E, Erisir F, Hizh C, Yener M, Cambaz B, et al. Aneurysmal bone cyst of the sphenoid bone. J Craniofacial Surg. 2002;13(3):411-4.

Rahbar M, Mardanpour MK. Gaint cell tumor of the sphenoid bone; Casp J Intern Med. 2010;1(4):155-8.

Aralasmak A, Aygun N, Westra WH, Yousem DM. Giant cell Reparative Granuloma of the Sphenoid Bone; Americ J Neuroradio. 2006;27(8):1675-7.

Sharma A, Garg A, Mishra NK, Gaikwad SB, Sharma MC, Gupta V, et al. Primary Ewing's sarcoma of the sphenoid bone with unusual imaging features: a case report. Clinic Neurol Neurosurg. 2005;107(6):528-31.

Singh GR, Choudhary V, Agrawal R. Primary Ewing Sarcoma of Sphenoid Bone with Intracranial Extension: A Common Tumour at an Uncommon Location.: JCDR. 2017;11(2):ED15.

Hayashi T, Kuroshima Y, Yoshida K, Kawase T, Ikeda E, Mukai M. Primary osteosarcoma of the sphenoid bone with extensive periosteal extension. Neurologia medico-chirurgica. 2000;40(8):419-22.

Chowhan AK, Rukmangadha N. Myxoid chondrosarcoma of sphenoidbone J Neurosci Rural Pract. 2012;3:395-8.

Gupta PK, Mital M, Dwivedi A, Gupta K. Metastasis of greater wing of sphenoid bone in bronchogenic carcinoma: A unusual case report. Journal of cancer research and therapeutics. 2011;7(2):195.

Hankinson TC, Kopell BH. Skull base tumors. 2015. Available from

Watts J, Box G, Galvin A, Brotchie P, Trost N and Sutherland T. Magnetic resonance imaging of meningiomas: a pictoral review Insights Imaging 2014;5(1):113-22.