Effects of Cyclosporine 0.05% ophthalmic solution on diagnostic parameters of dry eye disease

Authors

  • Maneesha Sethi Department of Ophthalmology, Acharya Shri Chander College of Medical Sciences and Hospital, Sidhra, Jammu, J&K, India
  • Amarjeet Singh Bali Department of Ophthalmology, Acharya Shri Chander College of Medical Sciences and Hospital, Sidhra, Jammu, J&K, India
  • P. Sadhotra Department of Ophthalmology, Acharya Shri Chander College of Medical Sciences and Hospital, Sidhra, Jammu, J&K, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20174160

Keywords:

Cyclosporine, Dry eye disease, Ocular surface disease index, Schirmer’s test

Abstract

Background: Dry eye is a multifactorial disease particularly prevalent in Asia for which there are several treatments. Among anti-inflammatory treatment, cyclosporine 0.05% is preferred therapy. Our study evaluated effects of cyclosporine 0.05% ophthalmic solution on the diagnostic tools of dry eye.

Material & Methods: A prospective study was carried out in ophthalmological outpatient department of ASCOMS and Hospital. Total 60 patients of dry eye disease who fulfilled the inclusion criteria were treated with cyclosporine 0.05% ophthalmic solution twice a day. The diagnostic parameters of dry eye were assessed at baseline, at month 1 and 3. Patients underwent Ocular Surface Disease Index (OSDI) score, Schirmer’s test, Tear film break up time (TBUT) .

Results: After three months, mean OSDI score was significantly improved (p < 0.001). There was significant improvement in mean Schirmer score (p < 0.001). Baseline TBUT also increased significantly (p < 0.001).

Conclusion: Cyclosporine 0.05% ophthalmic solution has significant effect on diagnostic parameters of dry eye disease.

 

 

References

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Published

2017-09-28

How to Cite

Sethi, M., Bali, A. S., & Sadhotra, P. (2017). Effects of Cyclosporine 0.05% ophthalmic solution on diagnostic parameters of dry eye disease. International Journal of Research in Medical Sciences, 5(10), 4289–4291. https://doi.org/10.18203/2320-6012.ijrms20174160

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Section

Original Research Articles