A comprehensive work up of various ventricular tachy-arrhythmias in relation to the underling cardiac disorder / status

Authors

  • Tusharkanti Patra Department of Cardiology, IPGMER, Kolkata, West Bengal, India
  • Prashant Kumar Department of Cardiology, IPGMER, Kolkata, West Bengal, India
  • Somnath Mukherjee Department of Cardiology, IPGMER, Kolkata, West Bengal, India
  • Anurag Passi Department of Cardiology, IPGMER, Kolkata, West Bengal, India
  • S. K. Saidul Islam Department of Cardiology, IPGMER, Kolkata, West Bengal, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20174161

Keywords:

Ischemic heart disease, Sudden cardiac death, Ventricular tachyarrhythmia

Abstract

Background: Main objective of the study is details work up of the patients of ventricular tachy-arrhythmias and to find out its association with any structural heart disease.

Methods: This institution based observational study was conducted in patients of documented sustained VT (ventricular tachycardia) with consecutive 102 patients.

Results: The mean age of the VT patients was 56.7 years and the number of male patients were 70 (69%). In our study, among 102 patients 45 patients were diabetic, 64 patients were hypertensive, 30 patients were current smoker, family history of heart disease was present in 25 patients and family history of SCD (sudden cardiac death) was present in 5 patients. Among the patients who presented with symptoms of ventricular tachy arrhythmia, 25 patients had EF (ejection fraction) above 40%, 36 had EF between 31 to 40% and only 2 had EF below 30%. CAG (coronary angiography) done in 98 patients and 16 had normal coronaries. 20, 16 and 46 patients had single, double and triple vessel disease respectively. 80 patients had coronary heart disease (78%), 20 patients among them had acute ischemic events and 60 had chronic ischemic disease. 12 patients didn’t have any structural heart disease.

Conclusions: Ischemic heart disease, acute or chronic, is the most common causes of ventricular tachyarrhythmia. male sex, diabetes mellitus, hypertension, smoking, family history of heart diseases or sudden cardiac death being the risk factors of coronary artery disease are also predisposing factors of ventricular tachyarrhythmia.

Author Biographies

Tusharkanti Patra, Department of Cardiology, IPGMER, Kolkata, West Bengal, India

DM RESIDENT, DEPARTMENT OF CARDIOLOGY

Prashant Kumar, Department of Cardiology, IPGMER, Kolkata, West Bengal, India

DM RESIDENT, DEPARTMENT OF CARDIOLOGY

Somnath Mukherjee, Department of Cardiology, IPGMER, Kolkata, West Bengal, India

DM RESIDENT, DEPARTMENT OF CARDIOLOGY

Anurag Passi, Department of Cardiology, IPGMER, Kolkata, West Bengal, India

DM RESIDENT, DEPARTMENT OF CARDIOLOGY

S. K. Saidul Islam, Department of Cardiology, IPGMER, Kolkata, West Bengal, India

ASSOCIATE PROFESSOR, DEPARTMENT OF CARDIOLOGY

References

Zheng ZJ, Croft JB, Giles WH, Mensah GA. Sudden cardiac death in the United States, 1989 to 1998. Circulation. 2001:104:2158-63.

Chugh SS, Reinier K, Teodorescu C, Evanado A, Kehr E, Al Samara M, et al. Epidemiology of sudden cardiac death: Clinical and research implications. Prog Cardiovasc Dis. 2008;51:213-28.

Zipes DP, Wellens HJ. Sudden cardiac death. Circulation. 1998;98:2334-51.

Engdahl J, Holmberg M, Karlson BW, Luepker R, Herlitz J. The epidemiology of out-of-hospital ‘sudden’ cardiac arrest. Resuscitation. 2002;52:235-45.

Joshi P, Islam S, Pais P, Reddy S, Dorairaj P, Kazmi K, et al. Risk factors for early myocardial infarction in South Asians compared with individuals in other countries. JAMA. 2007;297:286-94.

Ghaffar A, Reddy KS, Singhi M. Burden of non-communicable diseases in South Asia. BMJ. 2004;328:807-10.

Pellegrini CN, Scheinman MM. Clinical management of ventricular tachycardia. Curr Probl Cardiol. 2010;35:453.

Prystowsky EN, Padanilam BJ, Joshi S, Fogel RI. Ventricular arrhythmias in the absence of structural heart disease. J Am Coll Cardiol. 2012;59:1733.

Atkins DL, Everson-Stewart S, Sears GK. Epidemiology and outcomes from out-ofhospital cardiac arrest in children: the resuscitation outcomes consortium investigators epistry-cardiac arrest. Circulation. 2009;119:1484.

Wren C, O’Sullivan JJ, Wright C. Sudden death in children and adolescents. Heart. 2000;83:410.

Albert CM, Chae CU, Grodstein F. Prospective study of sudden cardiac death among women in the United States. Circulation. 2003;107:2096.

Albert CM, Mittleman MA, Chae CU. Triggering of sudden death from cardiac causes by vigorous exertion. N Engl J Med. 2000;343:1355.

Taylor AJ, Burke AP, O’Malley PG. A comparison of the Framingham risk index, coronary artery calcification, and culprit plaque morphology in sudden cardiac death. Circulation. 2000;101:1243.

Chugh SS, Reinier K, Singh T. Determinants of prolonged QT interval and their contribution to sudden death risk in coronary artery disease: the oregon sudden unexpected death study. Circulation. 2009;119:663.

Centers for Disease Control and Prevention (US), National Center for Chronic Disease Prevention and Health Promotion (US), Office on Smoking and Health (US): How tobacco smoke causes disease: The biology and behavioral basis for smoking-attributable disease: A report of the Surgeon General. Atlanta, Centers for Disease Control and Prevention, 2010. Available at www.cdc.gov/tobacco/data_statistics/sgr/2010/index.htm.

Samani NJ, Erdmann J, Hall AS. Genomewide association analysis of coronary artery disease. N Engl J Med. 2007;357:443.

Faber BC, Cleutjens KB, Niessen RL. Identification of genes potentially involved in rupture of human atherosclerotic plaques. Circ Res. 2001;89:547.

Downloads

Published

2017-09-28

How to Cite

Patra, T., Kumar, P., Mukherjee, S., Passi, A., & Islam, S. K. S. (2017). A comprehensive work up of various ventricular tachy-arrhythmias in relation to the underling cardiac disorder / status. International Journal of Research in Medical Sciences, 5(10), 4292–4296. https://doi.org/10.18203/2320-6012.ijrms20174161

Issue

Section

Original Research Articles