Published: 2016-12-16

Comparison of the efficiency of the nebulization of salbutamol, epinephrine and normal saline on treatment of bronchiolitis

Rakotomalala Rivo Lova Herilanto, Lovaniaina Ravelomanana, Andriatahirintsoa Emilson J. P. R., Tsifiregna Rosa Lalao, Ravelomanana Noeline


Background: Bronchiolitis is a frequent cause of hospitalization. Despite the frequency of this pathology, there is not a single, widely practiced evidence-driven treatment especially using of nebulization. Present purpose was to compare which is efficient: nebulized salbutamol, epinephrine or normal saline.

Methods: We have preceded to a prospective study from January 1st 2011 to March 31st 2012 including children between 29 days old and 2 years old.

Results: We have included 90 patients divided in three groups and received nebulized salbutamol, epinephrine or normal saline. There was no real difference in the variables of the groups: clinical score, oxygen saturation, heart rate, temperature and weight but the hospitalization duration was shorter in the group who have been cured by normal saline

Conclusions: This study shows that salbutamol, epinephrine and normal saline can be used in the same situation but the normal saline has more advantages because of his low coast and the absence of risk of side effects.


Bronchiolitis, Bronchodilatator, Epinephrine, Normal saline, Salbutamol

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