Retrospective analysis of biochemical profile of dengue infection in a tertiary care hospital

Denesh Narasimhan, Silpita Katragadda


Background: Dengue is an exceedingly common infection of the tropics. The aim of the research to study the biochemical parameters of serologically proven dengue cases.

Methods: The study included Dengue patients admitted in PSG Hospital between January 2011and December 2012.

Results: Analysis of aspartate aminotransferase results showed that 19.1% had two-fold rise, 13.3% had three-fold rise and 19.6% had more than threefold rise. Analysis of alanine aminotransferase showed that 35.7% had normal values, 14.95% had two-fold rise, 11.1% had three-fold rise and 11.5% had more than threefold rise. Serum proteins were normal in 35.7% and low in 19.6%. Analysis of serum albumin showed low values in 10.6% Serum sodium levels were low in 11.1% of patients. Albuminuria was positive in 53% of patients. Serum ionised calcium levels were low in 26.8% of patients.

Conclusions: The biochemical abnormalities noted in our study included include elevated liver enzymes, low sodium and ionised calcium levels, hypoalbuminemia and increased urine albumin excretion.


Dengue infection, Elevated liver enzymes, Hypocalcemia

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