Published: 2017-11-25

Prevalence of different components of the metabolic syndrome in type 2 diabetics attending tertiary care hospital in Himalayan region

Vikram Singh, Mridu Singh, Anil Joshi, Chitra Joshi


Background: There are enormous studies on various aspect of Diabetes and Metabolic syndrome, majority of studies are on urban population, few in rural area but very few for the population living in far flung hilly region of Himalaya. The aim was to find the prevalence of different components of metabolic syndrome in Type 2 diabetics living in the hills of Himalaya and to find correlation with obesity.

Methods: All the Type 2 Diabetic patients age 35 years and above attending the inpatients and out patient’s department of V. C. S. G. G. M. C and RI Srinagar, Uttarakhand from October 2012 to March 2013 were enrolled and were evaluated for metabolic syndrome by IDF (International Diabetes Federation) criteria.

Results: 128 diabetics were enrolled (76 males and 52 females), the prevalence of obesity in patients of type 2 diabetics was 45.3%. There was poor correlation between obesity and type 2 diabetes (correlation coefficient 0.08) The prevalence of metabolic syndrome was 40.6 % and high percentage (62%) had all five components of the syndrome.

Conclusions: The prevalence of obesity and Metabolic syndrome is relatively lower in Type 2 Diabetics of Shivalik range of Himalaya (Uttarakhand).


Himalayan region, Metabolic syndrome, Obesity, Type 2 diabetes mellitus

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Venkat Narayan KM, Zhang P, Kanaya AM. “Diabetes: the pandemic and potential solutions,” in Disease Control Priorities in Developing Countries, D. T. Jamison, J. G. Breman, A. R. Measham et al., Eds., Oxford University Press, New York, NY, USA, 2nd edition; 2006.

Qiao Q, Williams DE, Imperatore G, Venkat Narayan KM, and Tuomilehto J. “Epidemiology and geographyof type 2 diabetes mellitus,” in International Textbook of Diabetes Mellitus, R. A. de Fronzo, E. Ferrannini, H. Keen, and P. Zimmet, Eds., JohnWiley and Sons, Chichester, UK, 3rd edition, 2007. pp. 33-56.

Mohan V, Sandeep S, Deepa R, Shah B, Varghese C. Epidemiology of type 2 diabetes: Indian scenario. Ind J Med Res. 2007;125(3):217-30.

McKeigue PM, Shah B, Marmot MG. Relation of central obesity and insulin resistance with high diabetes prevalence and cardiovascular risk in South Asians. Lancet. 1991;337:382-6.

Mohan V, Sharp PS, Cloke HR, Burrin JM, Schumer B, Kohner EM. Serum immunoreactive insulin responses to a glucose load in Asian Indian and European Type 2 (noninsulin-dependent) diabetic patients and control subjects. Diabetologia. 1986;29:235-7.

Abate N, Chandalia M. Ethnicity and type 2 diabetes: focus on Asian Indians. J Diabetes Complications. 2001;15:320-7.

Joshi R. Metabolic syndrome - Emerging clusters of the Indian phenotype. J Assoc Physicians India. 2003;51:445-6.

Deepa R, Sandeep S, Mohan V. Abdominal obesity, visceral fat and type 2 diabetes- “Asian Indian phenotype. In: Mohan V, Rao GHR, editors. Type 2 diabetes in South Asians: Epidemiology, risk factors and prevention. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd; 2006 p. 138-52.

Chandalia M, Abate N, Garg A, Stray-Gunderson J, Grundy SM. Relationship between generalized and upper body obesity to insulin resistance in Asian Indian men. J Clin Endocrinol Metab. 1999;84: 2329-35.

Colditz GA. Weight as a risk factor for clinical diabetes in women. American Journal of Epidemiol. 1990;132:501-13.

Liu J. Impact of abdominal visceral and subcutaneous adipose tissue on cardiometabolic risk factors: The Jackson Heart Study. J Clinic Endocrinol Metabolism. 2010;95:5419-26.

Deedwania PC, Gupta R. Management issues in the metabolic syndrome. J Assoc Physicians India. 2006;54:797-810.

Misra KB, Endemann SW, Ayer M. Leisure time physical activity and metabolic syndrome in Asian Indian immigrants residing in northern California. Ethn Dis. 2005;15:627-34.

Gupta R, Deedwania PC, Gupta A, Rastogi S, Panwar RB, Kothari K. Prevalence of metabolic syndrome in an Indian urban population. Int J Cardiol. 2004;97(2):257-61.

Ramachandran A, Snehalatha C, Satyavani K, Sivasankari S, Vijay V. Metabolic syndrome in urban Asian Indian adults - a population study using modifi ed ATP III criteria. Diabetes Res Clin Practice. 2003;60:199-204.

Wasir JS, Misra A, Vikram NK, Pandey RM, Gupta R. Comparison of defi nitions of the metabolic syndrome in adult Asian Indians. J Assoc Physicians India. 2008;56:158-64.

Osuji CU, Nzerem BA, Dioka CE, Onwubuya El. Metabolic syndrome in newly diagnosed type 2 diabetes mellitus using NCEP-ATP III, the Nnewi experience. Nigerian J Clinic Practice. 2012;15(4): 75-480.

Pandya H, Lakhani JD, Patel N. Obesity is becoming synonym for diabetes in rural areas of India also – an alarming situation Int J Biol Med Res. 2011;2(2):556-60.

Ethiraj D, Bhansali A, Jaggi S, Dutta P, Jain S, Tiwari P, et al. Predictors of metabolic syndrome in Asian north Indians with newly detected type 2 diabetes. Indian J Med Res. 2009;129:506-14.

Raman R. Prevalence of Metabolic Syndrome and its influence on microvascular complications in the Indian population with Type 2 Diabetes Mellitus. Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetic Study (SN-DREAMS, report 14). Diabetology and Metabolic Syndrome. 2010,2:67.

Surana SP, Shah DB, Gala K, Susheja S, Hoskote SS, Gill N, et al. Prevalence of Metabolic Syndrome in An Urban Indian Diabetic Population Using The NCEP ATP III Guidelines. JAPI. 2008;56:865-8.