To study the association of high sensitivity C-reactive protein with metabolic syndrome

Authors

  • Vinod Saini Department of Medicine, Subharti Medical College, Swami Vivekananda Subharti University, Meerut, Uttar Pradesh, India
  • Abhishek Gupta Department of Medicine, Subharti Medical College, Swami Vivekananda Subharti University, Meerut, Uttar Pradesh, India
  • Mayank Arora Department of Medicine, Subharti Medical College, Swami Vivekananda Subharti University, Meerut, Uttar Pradesh, India
  • S. K. Virmani Department of Medicine, Subharti Medical College, Swami Vivekananda Subharti University, Meerut, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20180300

Keywords:

Dyslipidemia, hsCRP, Metabolic syndrome, Obesity

Abstract

Background: Metabolic Syndrome is a constellation of dyslipidemia (elevated triglycerides, low high-density lipoproteins (HDL)), elevation of arterial blood pressure (BP), dysregulated glucose homeostasis, and increased abdominal obesity.

Methods: We studied the association of high sensitivity C-reactive protein with metabolic syndrome by case-control method in our tertiary care hospital in West U.P.

Results: The mean age of cases and controls was 52.6 ± 7.7 and 51.4±7.0 years, respectively. There were 25 (50%) male and 25 (50%) female in case groups, and 27 (54%) males and 23 (46%) females in control group. Our analysis revelaed that there was a significant association between hs-CRP and the central obesity when compared in case-control group (3.57 vs 0.96 mg/L) (p value <0.001). There was no significant association between hs-CRP and high triglycerides, hypertension, diabetes, and reduced high density lipoprotein cholesterol.

Conclusions: Raised hsCRP level can be considered as a surrogate marker of chronic inflammation in patients with metabolic syndrome.

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Published

2018-01-24

How to Cite

Saini, V., Gupta, A., Arora, M., & Virmani, S. K. (2018). To study the association of high sensitivity C-reactive protein with metabolic syndrome. International Journal of Research in Medical Sciences, 6(2), 572–576. https://doi.org/10.18203/2320-6012.ijrms20180300

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Original Research Articles