A review of the association of mean platelet volume and red cell distribution width in inflammation
DOI:
https://doi.org/10.18203/2320-6012.ijrms20160001Keywords:
Hemogram parameters, Mean platelet volume, Red cell distribution width, InflammationAbstract
Simple hemogram parameters have been proposed as novel markers of inflammation recently. Two of these parameters are red cell distribution width (RDW) and mean platelet volume (MPV). Both MPV and RDW have been shown to be associated with inflammatory diseases. In this review, we aimed to discuss the clinical significance of these hemogram parameters in inflammatory states by reviewing the related studies in literature.
References
Aktas G, Alcelik A, Tekce BK, Tekelioglu V, Sit M, Savli H. Red cell distribution width and mean platelet volume in patients with irritable bowel syndrome. Przeglad gastroenterologiczny. 2014;9(3):160-3.
Aktas G, Alcelik A, Tekce BK, Sit M, Savli H, Tekce H, et al. Could Mean Platelet Volume and Red Cell Distribution Width Predict Vitamin B12 Deficiency? British Journal of Medicine and Medical Research. 2014;4(31):4965.
Aktas G, Sit M, Dikbas O, Tekce BK, Savli H, Tekce H, et al. Could Red Cell Distribution Width be a Marker in Hashimoto's Thyroiditis? Exp Clin Endocr Diab. 2014;122(10):572-4.
Aktas G, Alcelik A, Tekce BK, Savlı H, Uyeturk U, Kurt M et al. Mean Platelet Volume and Red Cell distribution width in Hepatosteatosis. National journal of medical research. 2013;3(3):264-6.
Sit M, Aktas G, Yilmaz EE, Hakyemez IN, Alcelik A, Kucukbayrak A. Platelet parameters in hepatic hydatid cysts. International journal of inflammation. 2013:593273.
Aktas G, Cakiroglu B, Sit M, Uyeturk U, Alcelik A, Savli H, et al. Mean Platelet Volume: A Simple Indicator of Chronic Prostatitis. Acta Medica Mediterr. 2013;29(3):551-4.
Aktas G, Sit M, Tekce H, Alcelik A, Savli H, Simsek T, et al. Mean platelet volume in nasal polyps. The West Indian medical journal. 2013;62(6):515-8.
Cakir L, Aktas G, Enginyurt O, Cakir SA. Mean Platelet Volume Increases in Type 2 Diabetes Mellitus Independent of Hba1c Level. Acta Medica Mediterr. 2014;30(2):425-8.
Demir R, Saritemur M, Ozel L, Ozdemir G, Emet M, Ulvi H. Red Cell Distribution Width Identifies Cerebral Venous Sinus Thrombosis in Patients With Headache. Clin Appl Thromb-Hem. 2015;21(4):354-8.
Hu ZD, Chen Y, Zhang L, Sun Y, Huang YL, Wang QQ. Red blood cell distribution width is a potential index to assess the disease activity of systemic lupus erythematosus. Clin Chim Acta. 2013;425:202-5.
Vaya A, Alis R, Hernandez JL, Calvo J, Mico L, Romagnoli M. RDW in patients with systemic lupus erythematosus. Influence of anaemia and inflammatory markers. Clin Hemorheol Micro. 2013;54(3):333-9.
Ramirez-Moreno JM, Gonzalez-Gomez M, Ollero-Ortiz A, Roa-Montero AM, Gomez-Baquero MJ, Constantino-Silva AB. Relation between red blood cell distribution width and ischemic stroke: a case-control study. Int J Stroke. 2013;8(6):E36.
Sadaka F, O'Brien J, Prakash S. Red cell distribution width and outcome in patients with septic shock. Journal of intensive care medicine. 2013;28(5):307-13.
Jo YH, Kim K, Lee JH, Kang C, Kim T, Park HM, et al. Red cell distribution width is a prognostic factor in severe sepsis and septic shock. Am J Emerg Med. 2013;31(3):545-8.
Lee JH, Chung HJ, Kim K, Jo YH, Rhee JE, Kim YJ, et al. Red cell distribution width as a prognostic marker in patients with community-acquired pneumonia. Am J Emerg Med. 2013;31(1):72-9.
Ozsu S, Abul Y, Gunaydin S, Orem A, Ozlu T. Prognostic Value of Red Cell Distribution Width in Patients With Pulmonary Embolism. Clin Appl Thromb-Hem. 2014;20(4):365-70.
Senol K, Saylam B, Kocaay F, Tez M. Red cell distribution width as a predictor of mortality in acute pancreatitis. Am J Emerg Med. 2013;31(4):687-9.
Seretis C, Seretis F, Lagoudianakis E, Gemenetzis G, Salemis NS. Is red cell distribution width a novel biomarker of breast cancer activity? Data from a pilot study. Journal of clinical medicine research. 2013;5(2):121.
Spell DW, Jones DV, Harper WF, Bessman DJ. The value of a complete blood count in predicting cancer of the colon. Cancer detection and prevention. 2004;28(1):37-42.
Speights VO, Johnson MW, Stoltenberg PH, Rappaport ES, Helbert B, Riggs MW. Complete blood count indices in colorectal carcinoma. Archives of pathology & laboratory medicine. 1992;116(3):258-60.
Baicus C, Caraiola S, Rimbas M, Patrascu R, Baicus A. Utility of routine hematological and inflammation parameters for the diagnosis of cancer in involuntary weight loss. Journal of investigative medicine: the official publication of the American Federation for Clinical Research. 2011;59(6):951-5.
Ozkalemkas F, Ali R, Ozkocaman V, Ozcelik T, Ozan U, Ozturk H, et al. The bone marrow aspirate and biopsy in the diagnosis of unsuspected nonhematologic malignancy: A clinical study of 19 cases. Bmc Cancer. 2005:5.
Seitanides B, Giakoumakis G, Tsakona C. Increased Red-Cell Volume Distribution Width in Patients with Bone-Marrow Metastases. J Clin Pathol. 1988;41(11):1246.
Cakal B, Akoz AG, Ustundag Y, Yalinkilic M, Ulker A, Ankarali H. Red Cell Distribution Width for Assessment of Activity of Inflammatory Bowel Disease. Digest Dis Sci. 2009:54(4):842-7.
Farkas K, Papp M, Nyári T, Nagy F, Szepes Z, Wittmann T, et al. Red blood cell distribution width in combination with serological markers can help in the differentiation between Crohn’s disease and ulcerative colitis. Open Gastroenterology Journal. 2010;4:1-4.
Balta S, Demirkol S, Hatipoglu M, Ardic S, Aydogan M, Celik T. Other inflammatory indicators should be kept in mind when assessing red cell distribution width in patients with pneumonia. Am J Emerg Med. 2013;31(7):1144-5.
Cakar M, Balta S, Demirkol S, Kurt O, Unlu M, Akhan M. Red Cell Distribution Width Should Be Assessed together with Other Inflammatory Markers in Daily Clinical Practice. Cardiology. 2013;124(1):60.
Bazzoni G, Dejana E, Delmaschio A. Platelet-Neutrophil Interactions - Possible Relevance in the Pathogenesis of Thrombosis and Inflammation. Haematologica. 1991;76(6):491-9.
Briggs C. Quality counts: new parameters in blood cell counting. International journal of laboratory hematology. 2009;31(3):277-97.
Bath PM, Butterworth RJ. Platelet size: measurement, physiology and vascular disease. Blood coagulation & fibrinolysis: an international journal in haemostasis and thrombosis. 1996;7(2):157-61.
Polinska B, Matowicka-Karna J, Kemona H. Assessment of the influence of the inflammatory process on the activation of blood platelets and morphological parameters in patients with ulcerative colitis (colitis ulcerosa). Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society. 2011;49(1):119-24.
Yuksel O, Helvaci K, Basar O, Koklu S, Caner S, Helvaci N et al. An overlooked indicator of disease activity in ulcerative colitis: mean platelet volume. Platelets. 2009;20(4):277-81.
Kapsoritakis AN, Koukourakis MI, Sfiridaki A, Potamianos SP, Kosmadaki MG, Koutroubakis IE et al. Mean platelet volume: A useful marker of inflammatory bowel disease activity. Am J Gastroenterol. 2001;96(3):776-81.
Kisacik B, Tufan A, Kalyoncu U, Karadag O, Akdogan A, Ozturk MA, et al. Mean platelet volume (MPV) as an inflammatory marker in ankylosing spondylitis and rheumatoid arthritis. Joint Bone Spine. 2008;75(3):291-4.
Shin WY, Jung DH, Shim JY, Lee HR. The association between non-alcoholic hepatic steatosis and mean platelet volume in an obese Korean population. Platelets. 2011;22(6):442-6.
Ozhan H, Aydin M, Yazici M, Yazgan O, Basar C, Gungor A et al. Mean platelet volume in patients with non-alcoholic fatty liver disease. Platelets. 2010;21(1):29-32.
Kucukbayrak A, Oz G, Findik G, Karaoglanoglu N, Kaya S, Tastepe I et al. Evaluation of platelet parameters in patients with pulmonary hydatid cyst. Mediterranean journal of hematology and infectious diseases. 2010;2(1):e2010006.
Beyan C, Kaptan K, Ifran A. Platelet count, mean platelet volume, platelet distribution width, and plateletcrit do not correlate with optical platelet aggegation responses in healthy volunteers. J Thromb Thrombolys. 2006;22(3):161-4.
Vizioli L, Muscari S, Muscari A. The relationship of mean platelet volume with the risk and prognosis of cardiovascular diseases. Int J Clin Pract. 2009;63(10):1509-15.
Dastjerdi MS, Emami T, Najafian A, Amini M. Mean platelet volume measurement, EDTA or citrate? Hematology. 2006;11(5):317-9.