Evaluation of the effects of Corchorus olitorius L. and Carapa procera in the treatment of obesity

Arsène M. Adon; Bognan A. A. J. Ackah; Guillaume Y. Yayé; Constantin O. Okou; Raoul K. K. Brahima; Joseph A. Djaman

doi:10.18203/2320-6012.ijrms20181259

Authors

Arsène M. Adon Laboratory of Cellular Biology, Pastor Institute, Abidjan, Côte d’Ivoire
Bognan A. A. J. Ackah Department of Biochemistry-Microbiology, UFR Agroforestry, Jean Lorougnon Guédé University, Côte d’Ivoire
Guillaume Y. Yayé Department of Biochemistry-Microbiology, UFR Agroforestry, Jean Lorougnon Guédé University, Côte d’Ivoire
Constantin O. Okou Department of Biochemistry-Microbiology, UFR Agroforestry, Jean Lorougnon Guédé University, Côte d’Ivoire
Raoul K. K. Brahima Department of Biochemistry-Microbiology, UFR Agroforestry, Jean Lorougnon Guédé University, Côte d’Ivoire
Joseph A. Djaman Laboratory of Pharmacodynamics-Biochemical, UFR Biosciences, University Félix Houphouët-Boigny, Abidjan-Cocody, Côte d’Ivoire

DOI:

https://doi.org/10.18203/2320-6012.ijrms20181259

Keywords:

Biochemical parameters, Carapa procera, Corchorus olitorius, Obesity

Abstract

Background: The obesity remains a pathology today which expands. It leads in its wake much pathology with very serious consequences. It is therefore necessary to take steps to curb this nutritional pathology. Thus, two plant species including Carapa procera and Corchorus olitorius have been tested to assess their effect on this pathology.

Methods: Aqueous extracts of Carapa procera bark and Corchorus olitorius roots were tested on rats and biochemical parameters were evaluated. Besides, a chemical characterization was led.

Results: These plant extracts contain bioactive molecules that have a regressive activity on the plasma levels of cholesterol, triglyceride and LDL-cholesterol. These bioactive molecules increase the level of HDL-cholesterol. These 2 species are non-toxic on renal, hepatic and pancreatic functions in view of the values of urea, creatinine and blood glucose.

Conclusions: Of these 2 extracts, the aqueous extract of Corchorus olitorius is more active.

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