Evaluation of peripheral lymphadenopathy by fine needle aspiration cytology: a one year study at tertiary centre

Authors

  • Pinal Chintan Shah Department of Pathology, Government Medical College, Surat
  • Chandni B. Patel Department of Pathology, Government Medical College, Surat
  • Vasudha Bhagat Department of Pathology, Government Medical College, Surat
  • Heta Modi Department of Pathology, Government Medical College, Surat

DOI:

https://doi.org/10.18203/2320-6012.ijrms20160016

Keywords:

Fine Needle Aspiration Cytology, Lymphadenopathy, Lymphoma

Abstract

Background: Lymphadenopathy is common presenting features in various non-neoplastic and neoplastic lesions. Fine needle aspiration cytology (FNAC) is simple, quick, inexpensive and minimally invasive technique that can be used as an outpatient procedure to diagnose them. The present study was undertaken to assess the various causes of lymphadenopathy through FNAC, and to see the distribution of lesions with respect to age and gender. To assess the diagnostic accuracy of lymph node fine needle aspiration (FNA) cytology in various non-neoplastic and neoplastic conditions.

Methods: Total 555 cases of the lymph node FNAC were studied from January 2014 to December 2014 in Cytopathology department of Government Medical College, Surat .The cytomorphologic features seen in the aspirates were analyzed and correlated with their etiology.

Results: In this study 555 cases of cervical lymphadenopathy were analysed. The age of the patients ranged from 5 months to 90 years of which 60.2% were males and 39.8% were females. Maximum numbers of cases 147(26.4%) were in the age group of 21- 30 years. The most common lesion encountered was tuberculous lymphadenitis 44.8% followed by metastatic tumors 31.3%, reactive lymph node 16.7%, acute lymphadenitis 5.4% and lymphoma 1.8%. Male showed predominance of metastatic carcinoma and lymphoma while chronic reactive hyperplasia and tuberculous lymphadenitis were equally distributed in both male & female.

Conclusions: FNAC is safe, rapid and cost effective method in establishing the diagnosis in large number of cases of lymphadenopathy. It can differentiate a neoplastic from a non-neoplastic process and therefore influence patient management preventing patient from being subjected to unnecessary surgery.

References

Orell SR. Introduction to Fine needle aspiration. In: Orell et al, editors. Manual and atlas of Fine needle aspiration cytology. Churchill Livingstone. 1999;2:1-85.

Shilpa G, Nataraju G. Pattern of Lymph Node Diseases in a Tertiary Level Referral Center: a cytological study of 943 cases. International Journal of Biological and Medical Research. 2013;4(3):3448-52.

Wilkinson AR, Mahore SD, Maimoon SA. FNAC in the diagnosis of lymph node malignancies: A simple and sensitive tool. Indian Journal of Medical and Pediatric Oncology. 2012;33(1):21-4.

Kumar N , Gupta BB, Sharma B, Kaushal M, Rewari BB, Sundriyal D. Role of fine-needle aspiration cytology in human immunodeficiency virus–associated lymphadenopathy: a cross-sectional study from northern India. Hong Kong Med J. 2015;21(1):39-44.

Mohanty R, Wilkinson A. Utility of Fine Needle Aspiration Cytology of Lymph nodes. IOSR Journal of Dental and Medical Sciences. 2013;8(5):13-8.

Shrivastav A, Shah HA, Agarwal NM, Santwani PM, Srivastava G. Evaluation of peripheral lymphadenopathy by fi ne needle aspiration cytology: A three year study at tertiary center. Journal of Dr. NTR University of Health Sciences. 2014;3(2):86-91.

Arif SH, Hassan MJ, Jain M, Verma AK, Nain M. Role of Imprint Cytology in Diagnosis of Lymph Node Lesions. Indian Medical Gazette. 2011:385-90.

Stewart CJR, Duncan JA, Farquharson M, Richmond J. Fine needle aspiration cytology diagnosis of malignant lymphoma and reactive lymphoid hyperplasia. J Clin Pathol. 1998;51:197-203.

Patel MM, Italiya SL, Patel RD, Dudhat RB, Kaptan KR, Baldwa VM. Role of Fine Needle Aspiration Cytology to Analyze Various Caus- es of Lymphadenopathy. Natl J Community Med. 2013;4(3):489-92.

Kumar H, Chandanwale SS, Gore CR, Buch AC, Satav VH, Pagaro PM. Role of fine needle aspiration cytology in assessment of cervical lymphadenopathy. Medical Journal of Dr. D.Y. Patil University. 2013;6(4):400-4.

Pandey P, Dixit A, Mahajan NC. The diagnostic value of FNAC in assessment of superficial palpable lymph nodes: a study of 395 cases. Al Ameen J Med Sci. 2013;6(4):320-7.

Hemalatha A, Udhay Kumar M, Harendra Kumar ML. A fine needle cytology of lyphnode: A mirror in the diagnosis of spectrum of lymphnode lesions. J clin biomed sci. 2011;1(4):164-72.

Madan Y, Joshi VS, Perumal RV. Fine Needle Aspiration Cytology for the Diagnosis of Tuberculous Lymphadenopathies. Indian journal of research. 2014;3(6).

Paliwal N, Thakur S, Mullick S, Gupta K. FNAC in Tuberculous Lymphadenitis: Experience From a Tertiary Level Referral Centre. Indian J Tuberculosis. 2011;58:102-7.

Wahid FI, Rehman H, Khan Q, Shahabi IK. Diagnostic value of fine needle aspiration cytology in diagnosis of non-thyroidal neck mass. JPMI. 2010;24(4):289-94.

Mamatha K, Arakeri SU. Clinicocytological study in evaluating the primary site of tumor in patients presenting with metastatic tumors in lymph node. Asian Journal of Pharmaceutical and Health Sciences. 2014;4(2):1001-5.

Mohan A, Thakral R, Kaur S, Singh S. Fine needle aspiration cytology in metastatic lymphadenopathy- A five year experience in Muzaffarnagar region. Journal of Advance Researches in Biological Sciences. 2013;5(2):172-6.

Babu GS, Ramesh G, Kashyap B, Suneela S, Hiremath SS, Murgud S. Cytohistopathological evaluation of the cervical lymph nodes by fine needle aspiration cytology. Journal of Cranio-Maxillary Diseases. 2014;3(2):101-5.

Ghartimagar D, Ghosh A, Ranabhat S, Shrestha MK, Narasimhan R, Talwar OP. Utility of fine needle aspiration cytology in metastatic lymph nodes. Journal of Pathology of Nepal. 2011;1:92-5.

Dowerah S, Kouli R, Karmakar T. A study of FNA findings of malignancy in lymph nodes with special emphasis on metastatic malignancy. International Journal of Basic Medical Science. 2014;5(4):68-71.

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Published

2016-12-24

How to Cite

Shah, P. C., Patel, C. B., Bhagat, V., & Modi, H. (2016). Evaluation of peripheral lymphadenopathy by fine needle aspiration cytology: a one year study at tertiary centre. International Journal of Research in Medical Sciences, 4(1), 120–125. https://doi.org/10.18203/2320-6012.ijrms20160016

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Original Research Articles