Published: 2018-03-28

A histopathological analysis of prevalence of various heart diseases: an autopsy study

Shilpa Garg, Sonia Hasija, Puja Sharma, Shivani Kalhan, Neerav Saini, Anam Khan


Background: Objective was to study the histopathological spectrum of heart diseases in autopsy specimens, that play a major role as cause of death.

Methods: During the period from October 2015 to October 2017. Total 170 medicolegal autopsies were received during this period. Out of 170, specimens of heart were 150. Nine specimens were autolyzed. So, 141 specimen of heart were included in the study. Gross and microscopic findings on H and E stained sections were studied.

Results: out of 141 cases, 78 cases showed atherosclerosis, 20 cases showed features of myocardial infarction, myocardial hypertrophy was found in 10 cases, 5 cases revealed myocarditis, pericarditis in 4 cases and one case each of infective endocarditis and aortic stenosis. In 22 cases, there was no identifiable cause of death even after complete gross and microscopic autopsy was performed.

Conclusions: Myocardial infarction due to atherosclerosis is probably the commonest finding in death cases subjected to medicolegal autopsies.


Coronaries, Heart, Post-mortem

Full Text:



Rao D, Sood D, Pathak P, Dongre SD. A cause of sudden cardiac deaths on autopsy findings: a four year report. Emergency. 2014;2(1):12-7.

Joshi C. Postmortem study of histopathological lesions of heart in cases of sudden death- an incidental finding. J Evid Based Med Healkthc. 2016;3(6):184-8.

Abedinzadeh N, Pedram B, Sadeghian Y, Nodushan SMHT, Gilasgar M, Darvish M, et al. A Histopathological Analysis of the epidemiology of coronary atherosclerosis: An autopsy study. Diagn Pathol. 2016;2(11)127.

Karanfil R, Gulmen MK, Hilal A. Evaluation of cardiac conduction system in sudden death cases. J For Med. 2013;27(1):17-28.

Papadodima SA, Emmanouil I, Pannagiotis S. Cardiovascular disease and drowning: autopsy and laboratory findings. Hellenic J Cardiol. 2007:48:198-205.

Ozdemir B, Celbis O, Onal R. Multiple organ pathologies underlying in sudden natural deaths. Medicine Science. 2012:1(1):13-26.

Wang HY, Zhao H, Song LF. pathological study of unexpected sudden death clustered in family or village in Yunnan province: report of 29 cases of autopsy. Zhonghua Yi Xue Za Zhi 2007;87(31):2209-14.

Basso C, Calabrese F, Corrado D. Post mortem diagnosis in sudden death victims: macroscopic, microscopic and molecular findings. Elseivier, cardiovascular research. 2001;50:290-300.

Drory Y, Turetz Y, Hiss Y. sudden unexpected deaths in person less than 40 years of age. Am J Cardiol. 1991;68:1388-92.

Kramer MR, Drory Y, Lev B. Sudden death in young Israeli soiliers: analysis of 83 cases. Isr J Med Sci. 1989;25:620-4.

Kumar, Abbas, Fausto. Robbins basic pathology. Indian Reprint; 8th Edition: ISBN:978-81-312-1036-9 Page No 416.