DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20181765

Study of clinical, electrocardiographic and echocardiographic profile in patients with chronic obstructive pulmonary disease

Rajan Chaudhari, Lalit Shrimali

Abstract


Background: Chronic obstructive pulmonary disease is the fourth leading cause of mortality worldwide. It is defined as a disease formal categorized by airflow limitation that is not fully reversible. Patients with chronic obstructive pulmonary disease (COPD) are at increased risk of cardiovascular disease. Electrocardiography (ECG) carries information about cardiac disease and prognosis in COPD patients. However, Echocardiography provides a rapid, noninvasive, portable, and accurate method to evaluate cardiac functions.

Methods: A 100 patients of COPD fulfilling the inclusion criteria coming to OPD/wards of Medicine, Gitanjali medical college and Hospital, Udaipur were recruited. They were staged by pulmonary function test (PFT) and evaluated by electrocardiography and echocardiography. Statistical analysis of correlation was done with chi square test and statistical significance was taken p<0.05.

Results: Mean age was 52.54±9.55 years, with male preponderance, male to female ratio 4.55:1. Mean duration of disease was 6.36±4.14 years. The common symptoms were Breathlessness (100%). Most common ECG and ECHO finding was RAD (52%) and PAH (54%) respectively. Statistically Right axis deviation and Poor ‘r’ wave progression was significantly correlated with disease severity by ECG findings while R.A. dilatation, R.V. dilatation and Pulmonary hypertension were significantly correlated with disease severity by ECHO findings (p<0.05).

Conclusions: COPD is more common in males and in the 5th and 6th decade of life. Most of the patients have fairly advanced disease at presentation. The incidence of abnormalities of ECG and echocardiography increases with COPD severity. ECG and echocardiography are better tools than clinical methods in detecting R.V. dysfunction in COPD.


Keywords


Chronic obstructive pulmonary disease, ECG, 2D-Echo

Full Text:

PDF

References


Silverman RJ. Chronic obstructive pulmonary disease. In: Kasper D. Harrisons manual of medicine. Fauci AS, Hauser SL, Longo DL, Jameson JL, Loscalzo J, editors. McGraw-Hill Medical Publishing Division. 2015;2:1700.

Chen JC, Mannino DM. Worldwide epidemiology of chronic obstructive pulmonary disease. Curr Opin Pulm Med. 1999;5:93-9.

Murray CJ, Lopez AD. Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. Lancet. 1997;349:1436-42.

Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. Executive summary. Medical Communications Resources, Inc. 2007:1-43.

Alfred P. Fishman. One Hundred Years of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2005;171:941-48.

Wagner GS. Marriott’s practical electrocardiography 11th Ed. New Delhi: Wolters Kluwer. 2011;218-22.

Dhadke VN, Dhadke SV, Raut N. Clinical profile in chronic obstructive pulmonary disease patients and their evaluation with spirometry and 2D echo Inter J Curr Res. 2015;7(2):12480-8.

Kutum US, Deb D, Sarma PC, Deb T, Pujar R. A study on chronic obstructive pulmonary disease (COPD) patients with reference to echocardiographic findings. JEMDS. 2015;4(103):16814-21.

Krishnan DR, Srihari B. A study on the severity of right ventricular dysfunction in correlation with the severity of lung dysfunction in chronic obstructive pulmonary disease patients-COPD. The Ame J Sci. and Med Res. 2015;1(1):112-9.

Suma KR, Srinath S. Electrocardiographic and echocardiographic changes in chronic obstructive pulmonary disease (COPD) of different grades of severity. J Evolution Med Dental Sci. 2015;4(30):5093-102.

Gupta S, Khastgir T, Gupta MP, Sethi KK, Manoharan S. Clinical, Haemodynamic and Echocardiographic study in chronic corpulmonale. JAPI. 1989;37(6):373-6.

Murphy ML, Hutcheson F. The electrocardiographic diagnosis of right ventricular hypertrophy in chronic obstructive pulmonary disease. Chest. 1974;65:622-7.

Tandon MK. Correlation of electrocardiographic features with airway obstruction in chronic bronchitis. Chest. 2004;63(2):146-8.