The relationship between vitamin D level and severity and control of bronchial asthma among adult Sudanese patients

Authors

  • Nadia A. Mustafa Department of Medicine, Aldamer Hospital, Aldamer city, River Nile State, Sudan
  • Omer E. Y. Elhag 2Alshaab Teaching Hospital, Khartoum, Sudan 3Department of Internal Medicine, Alneelain University, Khartoum, Sudan
  • Abdelrahman M. Abukanna Department of Medicine, Northern Border University, Saudi Arabia http://orcid.org/0000-0002-7877-8299
  • Ahmed H. Sulaiman Department of Medicine, Northern Border University, Saudi Arabia
  • Hafiz O. IbnIdris 3Department of Internal Medicine, Alneelain University, Khartoum, Sudan 4Department of Medicine, Northern Border University, Saudi Arabia

DOI:

https://doi.org/10.18203/2320-6012.ijrms20181753

Keywords:

Asthma control, Asthma severity, Bronchial asthma, Vitamin D deficiency

Abstract

Background: The aim of this study was to assess the relationship between vitamin D level and severity and control of bronchial asthma among adult Sudanese patients at Alshaab Teaching Hospital.

Methods: This prospective cross-sectional study, conducted at Alshaab Teaching Hospital, Khartoum Sudan in the period from June to August 2015. Eighty-six asthmatic patients participated in the study after taking their consent. Demographic data were collected using structured questionnaire, the clinical parameters of asthma severity and control were measured according to the criteria of Global Strategy for Asthma Management and Prevention 2014 of the Global Initiative for Asthma (GINA). Airway limitation was assessed using Peak Flow Meter. Three ml of blood was taken from each patient to measure vitamin D (25(OH)D) using enzyme-linked immunosorbent assay (ELISA) and data were analyzed using the statistical package for social science (SPSS) version 20.

Results: Normal serum 25(OH)D (30-50ng/ml) was found in only 2.3% of patients. The mean serum 25(OH)D level in patients with controlled asthma was 25.82±17.27ng/ml while in patients with uncontrolled asthma it was16.48±7.14ng/ml. (P value = 0.005). The mean serum 25(OH)D level in patients with severe asthma was 16.15±6.9ng/ml (P value = 0.151).

Conclusions: There was a positive correlation between vitamin D level and bronchial asthma control and a negative correlation with bronchial asthma severity among the study group.

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Published

2018-04-25

How to Cite

Mustafa, N. A., Elhag, O. E. Y., Abukanna, A. M., Sulaiman, A. H., & IbnIdris, H. O. (2018). The relationship between vitamin D level and severity and control of bronchial asthma among adult Sudanese patients. International Journal of Research in Medical Sciences, 6(5), 1649–1654. https://doi.org/10.18203/2320-6012.ijrms20181753

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Original Research Articles