Occurrence of neurocysticercosis in patients presenting with seizure and its serological evaluation

Authors

  • Khushbu Malhotra Department of Pediatrics, Teerthankar Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India
  • Mandeep Singh Department of Pediatrics, Glocal Institute of Medical Science, Saharanpur, Uttar Pradesh, India
  • Siddhant Sudanshu Department of Pediatrics, Teerthankar Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India
  • Vinod Kumar Department of Pediatrics, Teerthankar Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India
  • Utkarsh Sharma Department of Pediatrics, Teerthankar Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20184061

Keywords:

Del Brutt, Neurocysticercosis, Radiological evaluation, Seizure, Serology

Abstract

Background: Aims and objectives was to diagnose neurocysticercosis among the patient admitted with seizure in Pediatric Department of TMMRC and to correlate the serological and radiological findings.

Methods: A total of 100 patients presenting with recent onset seizures were recruited from Pediatric department of a local major tertiary care teaching hospital during the period 2016-2017. Brain imaging was performed in all the above cases. Serological assessment was done using ELISA kit. Diagnosis of neurrocysticercois was done using Del Brutto’s criteria.

Results: The recruited patients presented with generalized, simple partial, and focal seizures (68%, 21% and 11% respectively). NCC was diagnosed in 37 of 100 (37.0%) seizure cases based on imaging characteristics. There were 13% cases in whom, MRI showed calcified NCC/granuloma suggestive of NCC. In 24% cases, scolex suggestive of NCC was seen. A total of 15 (15%) cases were seropositive for Taenia. Using Del Brutto criteria, a total of 23% cases were diagnosed as probable NCC and 15% as definite neurocysticercosis. A total of 62% cases were confirmed as not having neurocysticercosis.

Conclusions: The findings of present study showed that neurocysticercosis still is a major diagnosis among children presenting with seizure from this endemic area. Neuroimaging was a useful tool in diagnosis and characterisation of NCC than serological tool. The study highlighted the need to create awareness regarding maintenance of hygiene and cleanliness.

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Published

2018-09-25

How to Cite

Malhotra, K., Singh, M., Sudanshu, S., Kumar, V., & Sharma, U. (2018). Occurrence of neurocysticercosis in patients presenting with seizure and its serological evaluation. International Journal of Research in Medical Sciences, 6(10), 3447–3453. https://doi.org/10.18203/2320-6012.ijrms20184061

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Original Research Articles