Occurrence of neurocysticercosis in patients presenting with seizure and its serological evaluation
Keywords:Del Brutt, Neurocysticercosis, Radiological evaluation, Seizure, Serology
Background: Aims and objectives was to diagnose neurocysticercosis among the patient admitted with seizure in Pediatric Department of TMMRC and to correlate the serological and radiological findings.
Methods: A total of 100 patients presenting with recent onset seizures were recruited from Pediatric department of a local major tertiary care teaching hospital during the period 2016-2017. Brain imaging was performed in all the above cases. Serological assessment was done using ELISA kit. Diagnosis of neurrocysticercois was done using Del Brutto’s criteria.
Results: The recruited patients presented with generalized, simple partial, and focal seizures (68%, 21% and 11% respectively). NCC was diagnosed in 37 of 100 (37.0%) seizure cases based on imaging characteristics. There were 13% cases in whom, MRI showed calcified NCC/granuloma suggestive of NCC. In 24% cases, scolex suggestive of NCC was seen. A total of 15 (15%) cases were seropositive for Taenia. Using Del Brutto criteria, a total of 23% cases were diagnosed as probable NCC and 15% as definite neurocysticercosis. A total of 62% cases were confirmed as not having neurocysticercosis.
Conclusions: The findings of present study showed that neurocysticercosis still is a major diagnosis among children presenting with seizure from this endemic area. Neuroimaging was a useful tool in diagnosis and characterisation of NCC than serological tool. The study highlighted the need to create awareness regarding maintenance of hygiene and cleanliness.
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