Pulmonary renal syndrome: treatment of acute renal failure secondary to double positive goodpasture syndrome


  • Rajkumar Prakashbhai Doshi Department of Medicine, Medical College Baroda, Gujarat
  • Viralkumar Patel SBKS Medical College, Waghodiya, Gujarat
  • Keyur Patel Department of Medicine, Medical College Baroda, Gujarat
  • Maulik Patel Nova Southeastern University, Florida




Acute renal failure, Goodpasture syndrome, Plasmapheresis


This is a case of a 34 year old female who presented with lower epigastric pain, flank pain and hematuria. Her symptoms started two days after being treated on Trimethoprim+Sulfamethoxazole for urinary tract infection. Worsening of her symptoms despite switching to Cephalexin prompted her to come to the emergency department. On admission, her creatinine was 5.3 mg/dL with potassium of 5.2 mEq/L and albuminuria of 100 mg/dL. Chest computed tomography (CT) without contrast revealed findings consistent with goodpasture disease. Biopsy of the kidney confirmed diffuse necrotizing and crescentic glomerulonephritis consistent with anti-glomerular basement membrane antibody disease. She was treated with plasmapheresis and steroids with complete resolution of symptoms at follow up.


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How to Cite

Doshi, R. P., Patel, V., Patel, K., & Patel, M. (2016). Pulmonary renal syndrome: treatment of acute renal failure secondary to double positive goodpasture syndrome. International Journal of Research in Medical Sciences, 4(1), 322–325. https://doi.org/10.18203/2320-6012.ijrms20160051



Case Reports