Pulmonary renal syndrome: treatment of acute renal failure secondary to double positive goodpasture syndrome

Rajkumar Prakashbhai Doshi; Viralkumar Patel; Keyur Patel; Maulik Patel

doi:10.18203/2320-6012.ijrms20160051

Authors

Rajkumar Prakashbhai Doshi Department of Medicine, Medical College Baroda, Gujarat
Viralkumar Patel SBKS Medical College, Waghodiya, Gujarat
Keyur Patel Department of Medicine, Medical College Baroda, Gujarat
Maulik Patel Nova Southeastern University, Florida

DOI:

https://doi.org/10.18203/2320-6012.ijrms20160051

Keywords:

Acute renal failure, Goodpasture syndrome, Plasmapheresis

Abstract

This is a case of a 34 year old female who presented with lower epigastric pain, flank pain and hematuria. Her symptoms started two days after being treated on Trimethoprim+Sulfamethoxazole for urinary tract infection. Worsening of her symptoms despite switching to Cephalexin prompted her to come to the emergency department. On admission, her creatinine was 5.3 mg/dL with potassium of 5.2 mEq/L and albuminuria of 100 mg/dL. Chest computed tomography (CT) without contrast revealed findings consistent with goodpasture disease. Biopsy of the kidney confirmed diffuse necrotizing and crescentic glomerulonephritis consistent with anti-glomerular basement membrane antibody disease. She was treated with plasmapheresis and steroids with complete resolution of symptoms at follow up.

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